1 / 21

Bone Development & Bone Growth

Bone Development & Bone Growth . Osteogenesis /ossification : The process of bone tissue formation In the embryo  formation of the bony skeleton Bone growth continues into early adulthood as we increase in size Later in life bone can grow in thickness. Formation of the Bony Skeleton .

zaina
Télécharger la présentation

Bone Development & Bone Growth

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Bone Development & Bone Growth

  2. Osteogenesis/ossification: The process of bone tissue formation • In the embryo formation of the bony skeleton • Bone growth continues into early adulthood as we increase in size • Later in life bone can grow in thickness

  3. Formation of the Bony Skeleton • Week 8 – fibrous membranes and hyaline cartilage begin to ossify. • Intramembranous ossification: development from fibrous membrane • Endochondral ossification: development from hyaline cartilage

  4. Intramembranous Ossification • Forms most bones of the skull and clavicles • All bones formed via this route flat bones • Fibrous CT from mesenchymal cells is framework on which ossification begins

  5. Four Major Steps: STEP ONE An ossification center appears in the fibrous CT membrane Mesenchymal cells cluster and become OSTEOBLASTS  forming ossification center

  6. Step Two Bone matrix (osteoid) is secreted within the fibrous membrane -osteoblasts secrete osteoid -trapped osteoblasts become osteocytes

  7. STEP THREE Woven bone and periosteum form -accumulating osteoid is laid down between embryonic blood, forming random network -result is a network of trabeculae. -vascularizedmesenchyme condenses on the external surface of the bone and forms periosteum

  8. Step Four • Bone collar of compact bone forms and red marrow appears • -Trabeculae just deep to the periosteum thicken, forming a bone collar that will later be replaced by mature bone • -Spongy bone (diploe), persist internally and its vascular tissue becomes red marrow

  9. Endochondral Ossification From the skull down, minus the clavicle!

  10. Begins in the second month of development. • More complex than intramembranous ossification • Begins in the center of long bone primary ossification center • Perichondrium becomes infiltrated with blood vessels • As a result osteoprogenitor cells become OSTEOBLASTS

  11. 1 • A BONE COLLAR FORMS AROUND THE DIAPHYSIS OF THE HYALINE CARTILAGE MODEL

  12. 2 • Cartilage in the center of the diaphysis calcifies and then cavitates

  13. 3 • The periosteal bud invades the internal cavity and spongy bone forms

  14. 4 • The diaphysis elongates and a medullary cavity forms

  15. 5 • The epiphyses ossify

  16. Postnatal Bone Growth • Infancy/youth long bones lengthen entirely by interstitial growth of the epiphyseal growth • Grow in thickness appositional growth

More Related