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Limited Impact of NEDD8 Pathway Inhibition on Intracellular Protein Turnover

This study by Soucy et al. (2009) explores how inhibiting the NEDD8 pathway differs from proteasome inhibition and its minimal effects on overall intracellular protein turnover dynamics. The research sheds light on the intricate processes regulating protein degradation within cells.

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Limited Impact of NEDD8 Pathway Inhibition on Intracellular Protein Turnover

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  1. NEDD8 pathway inhibition, in contrast to proteasome inhibition, minimally affects bulk intracellular protein turnover. TA Soucy et al. Nature458, 732-736 (2009) doi:10.1038/nature07884

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