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Effects of IFN-γ and MIBG on Cell Proliferation in Varying Concentrations

This study investigates the impact of different concentrations of IFN-γ and MIBG on cell proliferation. We analyzed proliferation rates (% of control) using various combinations, including IFN-γ at 10 U/ml and 100 U/ml with MIBG concentrations ranging from 1 µM to 20 µM. Results indicate significant variations in proliferation, suggesting a potential role for both agents in modulating cell growth. Understanding these interactions could provide insights into therapeutic strategies for conditions influenced by cell proliferation.

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Effects of IFN-γ and MIBG on Cell Proliferation in Varying Concentrations

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  1. A proliferation (% of control) 100 100 75 75 50 50 25 25 0 0 MIBG [µM] IFN (10U/ml) + MIBG (1µM) 1 5 10 100 25 IFN (10U/ml) + MIBG (5µM) IFN [U/ml] IFN (100U/ml) + MIBG (1µM) IFN (100U/ml) + MIBG (5µM) B proliferation (% of control) IFN (10U/ml) + MIBG (10µM) 10 10 20 100 50 IFN (10U/ml) + MIBG (20µM) IFN [U/ml] MIBG [µM] IFN (100U/ml) + MIBG (10µM) IFN (100U/ml) + MIBG (20µM)

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