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Official Full Name glucose-6-phosphate dehydrogenase

Official Full Name glucose-6-phosphate dehydrogenase

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Official Full Name glucose-6-phosphate dehydrogenase

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  1. g6pd Official Full Name glucose-6-phosphate dehydrogenase Background This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Synonyms G6PD; glucose-6-phosphate dehydrogenase; G6PD1; glucose-6-phosphate 1-dehydrogenase; Involved Pathway G6PD involved in several pathways and played different roles in them. We selected most pathways G6PD participated on our site, such as Pentose phosphate pathway, Glutathione metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with G6PD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein Pentose phosphate pathway

  2. PFKM; PFKMA; PRPS1L1; PGM1; GPIA; TALDO1; ALDOA; PFKL; H6PD; TKTL2 Glutathione metabolism GPX4A; GPX5; GSTT1; MGST1; GSTK1; MGST2; GCLM; MGST1.2; GSTP2; GSTT2B Metabolic pathways GK2; GLCE; MCAT; ALDH1A2; NSDHL; PI4KA; NDUFB3; PLA2G3; ALDH2; BCKDHA Carbon metabolism ME2; GM5506; FBP1B; pykF; PGAM1; GPR19; OGDHA; ENO1B; AGXTB; IDH2 Central carbon metabolism in cancer PIK3CG; PIK3CD; MAPK1; RET; C12orf5; PFKP; PDGFRB; PFKL; ERBB2; PDGFRA Protein Function G6PD has several biochemical functions, for example, NADP binding, glucose binding, glucose-6-phosphate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by G6PD itself. We selected most functions G6PD had, and list some proteins which have the same functions with G6PD. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function NADP binding Related Protein Related Protein FMO2; GAPDH; CRYZL1; ASPDH; DHFRL1; FMO3; G6PD; FMO1; CAT; GAPDHS Function Function glucose binding Related Protein Related Protein HK2; G6PDX; GYS1; SLC2A8; HK1; G6PD; SLC2A3; UGP2; HK3; PYGL Function Function glucose-6-phosphate dehydrogenase activity Related Protein Related Protein G6PDX; H6PD; G6PD Function Function identical protein binding Related Protein Related Protein DACT3; TNF; TP63; RALYL; SDCBP; DYNLT1A; ADIPOR1; TRP63; CLPP; SOX10 Function Function protein binding Related Protein Related Protein CCT7; KIFAP3; PLCG2; NOS3; ZC3HC1; INPP5B; C10orf81; FAF2; TXN2; NANOS2 Function Function protein homodimerization activity Related Protein Related Protein LGALS6; YARS2; PVR; SNRPC; KIAA1804; WWTR1; KLHL7; RBM44; GGCT; SNX9 Interacting Protein G6PD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and

  3. molecules interacted with G6PD here. Most of them are supplied by our site. Hope this information will be useful for your research of G6PD. SIRT2; HSPB1; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; ere_dna; FN1; p14340-pro_0000037966; CTR9; Snw1 G6PD Related Articles Maiga, B; Dolo, A; et al. Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali. MALARIA JOURNAL 13:-(2014). Liu, XD; Zhou, B; et al. BP5 regulated B cell development promoting anti-oxidant defence. AMINO ACIDS 46:209-222(2014).

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