html5-img
1 / 30

Hydrolysis of Glucose-6-Phosphate

Hydrolysis of Glucose-6-Phosphate. ∆Gº  = –3.3 kcal/mol. = –13.8 kJ/mol. High ∆Gº  Hydrolysis Compounds. ∆Gº  = –14.8 kcal/mol = –61.9 kJ/mol. High ∆Gº  Hydrolysis Compounds. ∆Gº  = –11.8 kcal/mol = –49.3 kJ/mol. High ∆Gº  Hydrolysis Compounds. ∆Gº  = –10.3 kcal/mol = –43 kJ/mol.

ethan-boyer
Télécharger la présentation

Hydrolysis of Glucose-6-Phosphate

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Hydrolysis of Glucose-6-Phosphate ∆Gº = –3.3 kcal/mol = –13.8 kJ/mol

  2. High ∆Gº Hydrolysis Compounds ∆Gº = –14.8 kcal/mol = –61.9 kJ/mol

  3. High ∆Gº Hydrolysis Compounds ∆Gº = –11.8 kcal/mol = –49.3 kJ/mol

  4. High ∆Gº Hydrolysis Compounds ∆Gº = –10.3 kcal/mol = –43 kJ/mol

  5. Phosphate Anhydrides (Pyrophosphates) ∆Gº = –7.3 kcal/mol = –30.5 kJ/mol

  6. Thiol Esters ∆Gº = –7.5 kcal/mol = –31.4 kJ/mol

  7. Thiol Esters Thiol ester less resonance-stabilized

  8. “High-Energy” Compounds • Large ∆Gº hydrolysis • Bond strain (electrostatic repulsion) in reactant • ATP • Products stabilized by ionization • Acyl-P • Products stabilized by isomerization • PEP • Products stabilized by resonance • Creatine-P

  9. “High-Energy” Compounds • “High-energy” compound is one with a ∆Gº below –6 kcal/mol (–25 kJ/mol)

  10. High-Energy Compounds

  11. Group Transfer Potential

  12. Lecture 25 Chemical Sense in Metabolism

More Related