What do we need to implant an embryo successfully

1. Implantation of an Embryo Wondering how Embryo Implantation works? Let’s take you through the process with this article… Before implantation, three other steps as well: 1.Sperm transport 2.Egg transport Fertilization and embryo development

2. What do we need to implant an embryo successfully? Successful implantation requires a competent blastocyst embryo interacting with a receptive endometrial lining. 6-10 days after the egg retrieval, implantation occurs. The 7-day-old embryo then attaches to the endometrium and begins gestation. At this stage, the embryo begins development and allows nutrients to flow in through the vitelline vesicle and the placenta. It is essential for the uterine line to acquire characteristics of thickness and appearance so that the embryo can implant in the endometrium and proceed towards an evolving pregnancy. Implantation of an embryo is definitely not an easy process. A proper uterine environment needs to be created where the endometrium and embryo can interact and grow. As mentioned previously in this article, for joining the endometrium, an embryo has to be in the blastocyst stage. Besides, the blastocyst must disassociate itself from the zona pellucida (outer layer surrounding the blastocyst) prior to implementation. Also, embryo quality can be evaluated only in patients undergoing IVF treatment. Ensuring the right movement of the embryo from the tube to the uterus in the natural fertilization stage is equally important. The innermost layer of the uterus- ‘an embryo’ is revamped after every menstrual cycle. This process is much needed to hold the pregnancy. In case of an implantation failure, the endometrium sheds in the form of periods. During your cycles, female hormones like estrogen and

3. progesterone, play their role in thickening the endometrium, which further undergoes multiple changes. It is very important for the endometrium to be receptive in order for the implantation to occur; which means the endometrial thickness should be between 7-10 mm. Besides, some molecules are also required to mediate a close dialogue with the embryo. Which molecules are responsible for interacting with the embryo? Cytokines Integrins Adhesion Did you know??? Cytokine molecule is a protein which regulates the interaction between diverse cells in the body. Implantation Window The implantation window has a duration of about 4 days. Generally, this window is most active from the 20th day until the 24th-day posts your periods. However, we should be aware that, often there are cases of women with the implantation window displaced leading to implantation failure and sterility. Remember, the synchrony between the endometrium and the embryo is the maximum when the endometrium changes from a nonreceptive to a receptive stage. What are the different phases of implantation?

4. Hatching Apposition Adhesion Invasion Get an insight into these phases of implantation with Medline Academic’s- ‘Basics of Embryology.’ Implantation of an embryo is an extremely complex process and involves factors which are complicated and requires extensive research. Training in embryology will definitely help overcome the shortages in the system and provide a useful outcome. Fertilization and implantation have been often used interchangeably, however, there’s a thin line of differences be Training with Medline Academics is the connection between gynaecology, biology and psychology. Now when it comes to foreign materials being inserted inside the body, you may notice certain discomfort initially. The same is the case with embryo implantation. Discomfort may exist similar to menstruation, but the issue does not persist for long. There are also cases where the women may not experience anything about the implantation until the pregnancy tests positive. There is much more to this wide topic. Embryo implantation is an interesting subject and there’s a great scope for embryologists in this

5. field. But choosing the right modules for embryology training is extremely important. Medline Academics has designed a comprehensive module with the best faculty in the field of embryology and hence is recommended for students pursuing reproductive medicine. Medline Academics is one of the finest institutes in the reproductive health space and offers a variety of courses under the same. To register yourself for the next batch of Basic and Advanced Embryology, visit our website www.medlineacademics.com