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This study examines the clinical features and survival times of NOD/SCID mice injected with either HT-SC or TOLEDO-SC cells through the tail vein. The data shows that animals experienced a significant decrease in body weight (15-20%) and immobility, leading to their sacrifice on day 29. The results highlight the impact of cell injection on the health and survival of NOD/SCID mice, emphasizing the need for careful monitoring and assessment in future research.
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Online Resource 1. Clinical features of the NOD/SCID mice injected with HT-SC or TOLEDO-SC cells via the tail vein. • Survival time values represent Mean ± SD. * Animals had to be sacrificed on day 29 because all of them showed a sudden • and simultaneous 15-20% reduction of body weight associated with immobility. Bosch et al. Online Resource 1