1 / 10

Gene Silencing Model

Gene Silencing Model. Gene Silencing Model. Eukaryotic Cell. Gene Silencing Model. Unloaded dicers. Gene Silencing Model. BUT - If ds RNA enters cell. Unloaded dicers ignore ss RNA. Gene Silencing Model. Dicers recognise ds RNA. Gene Silencing Model.

aida
Télécharger la présentation

Gene Silencing Model

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Gene Silencing Model

  2. Gene Silencing Model Eukaryotic Cell

  3. Gene Silencing Model Unloaded dicers

  4. Gene Silencing Model BUT - If ds RNA enters cell Unloaded dicers ignore ss RNA

  5. Gene Silencing Model Dicers recognise ds RNA

  6. Gene Silencing Model Dicers cleave ds RNA into 21 nt fragments

  7. Gene Silencing Model Loaded dicers transfer one 21 nt fragment to each RISC complex

  8. Gene Silencing Model Loaded dicers transfer one 21 nt fragment to each RISC complex

  9. Gene Silencing Model RISC complexes cleave ss RNA RISC complexes recognise complementary ss RNA

  10. Gene Silencing Model RNA destroyed and gene silenced!

More Related