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Outline: Bone and Bone Tissue Cartilage Tissue Orthopedic Fracture Fixation biostable polymers Total Joint Repla

Tissues. Biomaterial: a material that can function as a whole or part of a device to treat, assist, repair or replace an tissue, organ, or function of the body.. Tissue: Define:Organ: Define: . Types of Tissues:1. Epithelial tissue: covers the body surface and forms the lining

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Outline: Bone and Bone Tissue Cartilage Tissue Orthopedic Fracture Fixation biostable polymers Total Joint Repla

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    51. Wear of UHMWPE Acetabular Cup UHMWPE generates wear particles - billions to trillions wear particles produced (150,000 per step) - Wear rate = 0.1 mm/year - most are < 1 micron - Wear particles migrate to bone and cause osteolysis ___________________________ immune system response to wear particles bone modeling balance upset osteoclasts (bone resorption): increases osteoblasts (bone building) Causes loss of bone, implant loosening Why do wear particles reduce lifetime? Bone modeling balance think of bump on finger response to stress Loss of bone around implant stem = slippage = painWhy do wear particles reduce lifetime? Bone modeling balance think of bump on finger response to stress Loss of bone around implant stem = slippage = pain

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