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Impact of TGF-β on M1 Macrophage Activation and Gene Expression Over Time

This study investigates the effects of TGF-β at 24, 48, and 72 hours on M1 macrophages (M1-4HSC). We analyze gene expression changes, specifically focusing on PDGF receptors (PDGF-Rα, PDGF-Rβ) and transcription factors c-fos and c-jun, alongside rhoA signaling pathways. Understanding these interactions may provide insights into macrophage behavior in various pathological conditions and potential therapeutic approaches.

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Impact of TGF-β on M1 Macrophage Activation and Gene Expression Over Time

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  1. + 24h TGF-b + 48h TGF-b + 72h TGF-b M1-4HSC M-HT PDGF-R PDGF-R c-fos c-jun rhoA

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