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Lower-limb performance disparities: Implications for exercise prescription in multiple sclerosis

Lower-limb performance disparities: Implications for exercise prescription in multiple sclerosis. Rebecca D. Larson, PhD; Kevin K. McCully, PhD; Daniel J. Larson, PhD; William M. Pryor, MS; Lesley J. White, PhD. Aim

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Lower-limb performance disparities: Implications for exercise prescription in multiple sclerosis

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  1. Lower-limb performance disparities: Implications for exerciseprescription in multiple sclerosis Rebecca D. Larson, PhD; Kevin K. McCully, PhD; Daniel J. Larson, PhD; William M. Pryor, MS; Lesley J. White, PhD

  2. Aim • Examine unilateral lower-limb exercise tolerance during fixed-load cycling to quantify performance disparities of the legs in individuals with multiple sclerosis (MS). • Relevance • Evidence suggests that individuals with MS exhibit bilateral differences in strength and function. • Such differences may explain higher energy demand during exercise.

  3. Method • 8 individuals with relapsing-remitting MS and 7 controls performed submaximal single-leg cycling.

  4. Results • Individuals with MS: • Performed significantly more work with stronger leg than weaker leg. • Control group: • Displayed no statistical differences between limbs.

  5. Conclusion • Results highlight need for individualized exercise testing when prescribing training programs for those with MS.

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