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MICROSPHERES AS A NOVEL DRUG DELIVERY SYSTEM

For more presentations and information visit http://www.pharmaxchange.info. MICROSPHERES AS A NOVEL DRUG DELIVERY SYSTEM . Omkar. T, Vikas College of Pharmacy, Vissannapet, Andhrapradesh. For more presentations and information visit http://www.pharmaxchange.info. Introduction .

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MICROSPHERES AS A NOVEL DRUG DELIVERY SYSTEM

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  1. For more presentations and information visit http://www.pharmaxchange.info MICROSPHERES AS A NOVEL DRUG DELIVERY SYSTEM Omkar. T, Vikas College of Pharmacy, Vissannapet, Andhrapradesh

  2. For more presentations and information visit http://www.pharmaxchange.info Introduction

  3. For more presentations and information visit http://www.pharmaxchange.info Methods of Preparation • Single emulsion technique • Double emulsion technique • Polymerization technique • Spray drying technique • Solvent extraction

  4. For more presentations and information visit http://www.pharmaxchange.info white microspheres yellow microspheres bi-chromal black microspheres pinkcoated microspheres green microspheres transparent microspheres colour metched

  5. Synthetic polymers:- Parenteral preparations-- Poly alkyl cyanoacrylates Narcotic antagonists, cancer drugs-- Poly lactic acid—sustained release ocular delivery-- Poly anhydrate microspheres Natural polymers Albumin – Targeted drug delivery to Tumor cells. Gelatin microspheres – interferon, phagocytes. Starch – more -OH groups, so all drugs For more presentations and information visit http://www.pharmaxchange.info Applications

  6. For more presentations and information visit http://www.pharmaxchange.info • In vaccine therapy • Monoclonal antibody therapy • Chemo embolisation • In radiology treatment for cancer • In cosmetic technologies

  7. For more presentations and information visit http://www.pharmaxchange.info Future: Atrigel Drug Delivery System • The Atrigel® drug delivery system consists of biodegradable polymers dissolved in biocompatible carriers.  Pharmaceuticals may be blended into this liquid delivery system at the time of manufacturing or, depending upon the product, may be added later by the physician at the time of use.  When the liquid product is injected into the subcutaneous space through a small gauge needle or placed into accessible tissue sites through a cannula, water in the tissue fluids causes the polymer to precipitate and trap the drug in a solid implant. The drug encapsulated within the implant is then released in a controlled manner as the polymer matrix biodegrades with time.

  8. For more presentations and information visit http://www.pharmaxchange.info Thank you

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