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Pilot WP 6.4 Genomics & colon cancer

Pilot WP 6.4 Genomics & colon cancer. HNPCC-register. Today: Paper based. 4 genetic dept. 4 laboratories 50 surg.dept. >20 gyn.dept. Future Aims: Interoperability Communication Further IT-support Web-reporting of data. HNPCC-register. Today: Paper based. Future Aims:

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Pilot WP 6.4 Genomics & colon cancer

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  1. Pilot WP 6.4 Genomics & colon cancer

  2. HNPCC-register Today: Paper based 4 genetic dept. 4 laboratories 50 surg.dept. >20 gyn.dept. Future Aims: Interoperability Communication Further IT-support Web-reporting of data

  3. HNPCC-register Today: Paper based Future Aims: Interoperability Communication Further IT-support Web-reporting of data

  4. Web Service Provider Web Server Danish Health Data Network Vali-dation HNPCC DB Front end Web Page Client Web Service Client HTML Web Service Laboratory / Surgery Dep. / Genetic Dep. Not part of InfoBioMed

  5. Invited departments Genetic Department Surgical Department Århus Odense Vejle Århus Ålborg Hvidovre Laboratory Hvidovre Ålborg Hvidovre Odense Herning Århus Copenhagen 100% functioning IP-addresses

  6. Århus Vejle Odense Ålborg Århus Hvidovre Hvidovre Herning Ålborg Odense Århus Hvidovre Copenhagen Genetic Department Surgical Department Laboratory

  7. Max Bergren II:1 Odense Vejle Århus Ålborg Århus Hvidovre Hvidovre Odense Ålborg Århus Hvidovre Herning Copenhagen Genetic Department Surgical Department Laboratory

  8. Århus Vejle Odense Ålborg Århus Hvidovre Hvidovre Herning Ålborg Odense Århus Hvidovre Copenhagen Genetic Department Surgical Department Laboratory

  9. Århus Vejle Odense Hvidovre Århus Ålborg Hvidovre Ålborg Odense Århus Hvidovre Herning Copenhagen Genetic Department MLH1, exon4, c.350C>T, p.T117M Surgical Department Laboratory

  10. HHUD – evaluation

  11. International HL7 Interoperability Conference IHIC 2006 August 24-25, 2006, Cologne, Germany

  12. FORTH Family Information HL7v3 model

  13. FORTH Individual Information HL7v3 model

  14. Example: CDA for Surveillance messages

  15. Summary • HL7 interoperability can eliminate heterogeneity and speed-up reporting of laboratories, surgery, and genetic counseling departments to the Danish HNPCC registry. • In the long run it can also facilitate cooperation among HNPCC registries in Europe. • We have experimented with the HL7 v3 tools, Family History Model of the Clinical Genomics SIG and CDA release 2 to facilitate information exchange and promote interoperability.

  16. Conclusions HL7 v3 tools are useful but require a long time of work. Interoperability of the result is limited. • Family History topic is the most promising solution in the long term. • collaboration with the Clinical Genomics SIG is envisioned to share understanding and reach consensus. • CDA release 2 currently provides early feedback and max flexibility among the solutions we investigated. • Implementation guides should be developed and shared with the community for the CDA and the Family History model. • they are the key to interoperability!

  17. FORTH UPM Evaluation HHUD Custodix ISCIII Aveiro WEB HNPCC FUNEN XML/HL7 Implementation SNP2005 Leicester 2007 2005 2006

  18. Specific output WP 6.4 • Current status data exchange HNPCC • 4 XML standards on clinical content • Design of XML documents • WEB service client • Implementation & evaluation of WEB-client • Ethical, legal and security issues • Early HL7 and CDA experience • Dissemination experience

  19. Experience ??

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