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Dementia encompasses various types, each with distinct characteristics. Alzheimer's disease is the most prevalent, accounting for 60-80% of cases. Creutzfeldt-Jakob disease, a fatal condition caused by prion misfolding, and dementia with Lewy bodies features Parkinsonian symptoms. Frontal-temporal dementia includes progressive aphasia and lacks notable brain anomalies. Mixed dementia combines traits of Alzheimer's and other types like vascular dementia, impacting judgement over memory. Normal pressure hydrocephalus can lead to walking difficulties and urinary issues. Understanding these types is crucial for diagnosis and management.
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Common Types of Dementia Type Some Attributes Alzheimer’s disease Most common type; 60-80% of dementia cases. Creutzfeldt-Jakob Fatal disorder that causes dementia; due todisease (CJD) protein misfolding (e.g., prions); linked to mad cow disease. Dementia with Lewy Like AD but with Parkinsonian-like symptoms; bodies (DLB) involves Lewy body (alpha-synuclein) deposits. Frontal-temporal Progressive aphasia, Pick’s disease attributes; dementia (FTD) no evident microscopic anomalies in brain; also called frontal-temporal lobar dementia (FTLD) Mixed dementia AD attributes plus one other such as vascular dementia or DLB; may be more common than previously thought. Normal pressure Difficulty walking, controlling urination; due to hydrocephalus fluid build-up in the brain. Parkinson’s Results in dementia like DLB or AD; due to diseaseLewy body (alpha-synuclein) deposits in brain. Vascular dementia Due to bleeding, blockage of blood vessels in the brain; initial effect: impaired judgement and ability to plan rather than memory loss. • Table 3.1 from: • “The Alzheimer’s Epidemic: Searching for Causes and a Cure • by Danton H. O’Day, 2013