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PHARMACOLOGICAL STRESS ECHOCARDIOGRAPHY. Dr. Benny J Panakkal Senior Resident Dept. of Cardiology Medical College, Kozhikode. Understanding Basic Concepts. Ischemia Cascade The answer to the Question “Why Echo”. Why Echo in comparison to SPECT, PET etc. Stressors in Stress Testing.
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PHARMACOLOGICAL STRESS ECHOCARDIOGRAPHY Dr. Benny J Panakkal Senior Resident Dept. of Cardiology Medical College, Kozhikode
Ischemia Cascade The answer to the Question “Why Echo”
Exercise as a Stressor • Prototype of Demand driven ischemic stress
Situations where Pharmacological Stress is preferred to Exercise Stress
Adverse Effects and Complications
Imaging Equipment and Acquisition
Quad screen Format Normal response to Exercise, Dobutamine or Pacing Stress Echo
Excessive Gain setting spoiling the Endocardial border definition
Applying Strain Rate Imaging in Stress Echo Low dose Dobutamine
Applying Strain Rate Imaging in Stress Echo High dose Dobutamine
Special clinical conditions and target endpoints in Stress Echo
Diagnostic and Prognostic value of CFR during Vasodilator testing
Wall motion scoring and attribution to coronary vascular territories
Differential responses to Exercise and Dobutamine Stress Echo
Statistics, Studies The Comparison
Single Centre Analysis ( >50,000 studies ) – Mayo Clinic SVT and AF are more common than VT/VF
Diagnostic Accuracy - Overall Sensitivities in CAD subtypes Pellikka PA: Stress echocardiography for the diagnosis of coronary artery disease: Progress towards quantification. CurrOpinCardiol 20:395, 2005. Armstrong WF, Zoghbi WA: Stress echocardiography: Current methodology and clinical applications. J Am CollCardiol 45:1739, 2005