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The smallpox virus, a member of the Orthopoxvirus genus, features a complex structure known as the virion. Its outer envelope is crucial for viral entry into host cells. Inside, the viral genome, composed of double-stranded DNA, carries the genetic instructions necessary for replication and infection. Enzymes encoded by this genome play vital roles in the virus's life cycle, including evasion of the host immune response and the replication of viral DNA. This overview highlights the intricate interactions between the virus's components.
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