1 / 12

Guy Kleinmann, MD 1 Shmuel Ben-Elihau, DVM 2

Biocompatibility of a New Hydrophobic Acrylic Material for Fabrication of IOLs. Guy Kleinmann, MD 1 Shmuel Ben-Elihau, DVM 2. Ophthalmology Department, Kaplan Medical Center Harlan Biotech Israel. Guy Kleinmann is a consultant for Hanita Lenses. Purpose.

buzz
Télécharger la présentation

Guy Kleinmann, MD 1 Shmuel Ben-Elihau, DVM 2

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Biocompatibility of a New Hydrophobic Acrylic Material for Fabrication of IOLs Guy Kleinmann, MD1 Shmuel Ben-Elihau, DVM2 • Ophthalmology Department, Kaplan Medical Center • Harlan Biotech Israel Guy Kleinmann is a consultant for Hanita Lenses

  2. Purpose To evaluate the biocompatibility of a new hydrophobic IOL material; the Benz-HF1 Natural Yellow, Using the SeeLens IOL (Hanita, Israel) as a platform

  3. Methods • 10 NZW rabbits • Each rabbit was randomly implanted with the new hydrophobic IOL in one eye and B-lens IOL (Hanita, Israel)in the fellow eye • Follow up: 1D, 1W, 1M, 3M, 6M • Each follow up included: • Photography • Slit lamp clinical evaluation

  4. Methods – cont. • At the end of the study: • Enucliation of the eye • Explantion of the lens • Histological evaluation of the eye • SEM/EDS of the explanted IOLs • Analysis of the explanted IOLs: • Light microscopy analysis (all IOLs) • Transmission spectrum (half of the IOLs) • Scanning electron microscopic + energy dispersive x-ray (SEM/EDX) (half of the IOLs) • Two non-implanted IOLs of each IOL served as negative controls

  5. Results: Macroscopic 1 month New Hydrophobic Control

  6. ResultsSlit lamp evaluation 1 month 3 months 6 months Control New Hydrophobic

  7. Results 6 months slit lamp evaluation

  8. Histopathological results

  9. Histology summary • No treatment related nor material related changes were noted • All reported changes had comparable incidence in both groups

  10. SEM/EDS of explanted IOLs Control New Hydrophobic

  11. Explanted IOLs- summary The Investigated hydrophobic study IOLs were superior in comparison to the control lenses

  12. Discussion • The Benz-HF1 Natural Yellow material was found to be superior to the hydrophilic IOL in all the IOL analysis parameter • No difference between the groups was found in the clinical and histological evaluations Conclusion The Benz-HF1 Natural Yellow material, using the SeeLens IOL platform (Hanita, Isreal), demonstrated excellent biocompatibility in the Rabbit model of ocular implantation test

More Related