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Bacterial genetics primarily revolves around the structure of their genome, which is typically a single double-stranded circular DNA molecule. For instance, Escherichia coli (E. coli) has a chromosomal DNA that comprises approximately 4.6 million nucleotide pairs, encoding around 4,300 genes. The DNA is tightly coiled, forming a dense area known as the nucleoid. This unique organization plays a crucial role in bacterial cell function, replication, and gene expression, providing insights into their biology and potential applications in biotechnology and medicine.
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