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Discover the wonders of the immune system's defense mechanisms, from the physical barriers of the skin to the powerful white blood cells and defense proteins that protect our bodies from pathogens. Learn about the roles of phagocytes, lymphocytes, antibodies, interferon, and the benefits of vaccination in preventing infections. Explore the world of pathogens, including viruses, bacteria, fungi, protozoans, and parasites, and how they can be transmitted through various means. Dive into this fascinating realm of biological protection and understand the complex workings of our immune system.
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The Skin • 1st line of defense: physical barrier • Oils & sweat destroy some pathogens • Some cells burst • Some cells shrivel
Mucus Membranes • Coat the openings of the body • Nose, mouth, ears, eyes, genitals, anus • Lined with cilia & sticky fluids to trap pathogens
White Blood Cells • Job: Search & destroy • Phagocytes: surround & engulf invaders • Phagocytosis • Lymphocytes: • T cells: destroy infected body cells • B cells: Inactivate invaders
Defense Proteins • Complimentary Proteins • Weaken cell membrane • Attract phagocytes • Cause microbes to stick to wall of blood vessel
Defense Proteins • Antibodies • Made by B cells • Bind to cell membrane of pathogen • Prevents pathogen from binding to host cells • Causes pathogens to clump • More susceptible to phagocytes • Weakens the cell membrane • Causes them to burst
Defense Proteins • Interferon • Produced by virus infected cells • Stimulates uninfected cells to create infection preventing enzymes
Vaccination • Prevents infections (not a cure) • Memory cells developed without actually getting the disease • Vaccine • Contains antigens of a pathogen • Weakened pathogen is injected • Stimulates the production of memory cells • Speeds up immune response if you encounter the unweakened virus
Pathogens • Defined: microorganisms that cause disease • Viruses: turn cells into virus making factories • Bacteria: prokaryotes that can release toxic chemicals • Fungi: pierce cells and absorb the nutrients • Protozoans: single cells protista (eukaryotes) • Parasites: grow and feed on a host
Pathogens (contd) • Some carried by wind, water, direct contact, indirect contact… • Some carried by vectors • Vector: object that carries a pathogen • Examples: • Malaria – mosquitos carry the protozoan • Black Death – carried by flea’s of mice • West Nile Virus – carried by birds, but spread by mosquitos