Transforming Static CT in Gated PET/CT Studies to Multiple Respiratory Phases

1. Transforming Static CT in Gated PET/CT Studies toMultiple Respiratory Phases M Dawood, F Büther, N Lang, X Jiang, KP Schäfers Department of Nuclear Medicine, University Hospital Münster, Germany

2. PET/CT Positron Emission Tomography / Computed Tomography M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

3. PET Positron Emission Tomography β+-decay of 18F: 18F → 18O + e+ + νe Pair annihilation: e+ + e-→ 2 γ M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

4. Sinogram Detector 1 φ s LOR LOR φ Detector 2 s M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

5. Reconstruction M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

6. Attenuation M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

7. Problem Spatial non-correspondance between PET and CT due to motion M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

8. Solution Divide the PET data into respiratory phases, and transform the static CT to corresponding phases M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

9. Gating … M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

10. Gating: Acquiring the respiratory signal M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

11. Optical Flow A method to estimate deformation between image frames Independent of the form and type of movement between the frames Non-rigid and pixel-based M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

12. Combined Local/Global Minimize fLG M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

13. Discontinuity Preserving Non-Quadratic Non-Quadratic approach allows better approximation than least squares Discontinuity preservation allows better estimation across organ boundaries Minimize fD M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

14. Demonstration Lukas/Kanade Horn/Schunck Bruhn Non-Linear Discontinuity Preserving Result M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

15. Results: Gated data M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

16. Results: Attenuation Without Motion Correction M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

17. Results: Transformed Attenuation Map M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

18. Results: Attenuation With Transformed Map M. Dawood et al. Motion correction in 3d PET/CT with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.