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Transcription in Eukaryotes

Transcription in Eukaryotes. Class II promoters:. *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE) *Upstream Promoter Element. Transcription Initiation in Eukaryotes. General Transcription Factors and the Pre-initiation complex:.

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Transcription in Eukaryotes

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  1. Transcription in Eukaryotes Class II promoters: *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE) *Upstream Promoter Element

  2. Transcription Initiation in Eukaryotes General Transcription Factors and the Pre-initiation complex:

  3. Transcription Initiation in Eukaryotes TBP binding:

  4. Transcription Initiation in Eukaryotes

  5. Transcription Initiation in Eukaryotes

  6. Elongation of Transcription in Eukaryotes Schematic Model

  7. RNA processing in eukaryotes Addition of poly A tail Addition of 5’cap Splicing Polyadenylation *CstF *CPSF *PAP *PABP

  8. Torpedo model for transcription termination

  9. Transcript Processing Formation of the 5’ cap *RNA triphosphatase *guanylyl transferase *methyl transferase

  10. Functions of the Cap and Tail • Protection • Translatability • Transport • Splicing

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