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Neural Tube Deficiency

Neural Tube Deficiency. Neural Tube Facts. most common birth defects approximately one in 1,000 live births in the United States. opening in the spinal cord or brain that occurs very early in human development. early spinal cord of the embryo begins as a flat region

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Neural Tube Deficiency

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  1. Neural Tube Deficiency

  2. Neural Tube Facts • most common birth defects • approximately one in 1,000 live births in the United States. • opening in the spinal cord or brain that occurs very early in human development. • early spinal cord of the embryo begins as a flat region • 28 days after the baby is conceived the spinal cord begins to roll into a neural tube • When the neural tube does not close completely, an NTD develops. • NTDs develop before most women know they are even pregnant.

  3. Spinal Bifida • Spinal Bifida

  4. Folic Acid Supplement • 50-70% of NTDs can be prevented when women supplement their diet with folic acid, a water-soluble B vitamin • women of childbearing age eat a diet high in folic acid • take a multivitamin with 0.4mg of folic acid each day, one month prior to conception through the first three months of pregnancy.

  5. Sources of Folate

  6. Detection of NTD • Maternal Serum Alpha Fetoprotein (MSAFP), • woman's blood tested at approximately 16-18 weeks of pregnancy • Looking for levels of Alpha-fetaprotein • High level suggest Neural Tube Defect • Low Levels suggest chromosome abnormalties (ex. Down Syndrome)

  7. Additional tests to detect NTD • High Resolution Ultrasound, which may detect an NTD visually after approximately 18 weeks of pregnancy. • Amniocentesis, a test that samples the amniotic fluid (fluid that surrounds the baby) after 15 weeks of pregnancy.

  8. Treatment for NTD • Treatment of neural tube defects • Surgery -soon after birth • within the first 24 to 48 hours— • to protect the exposed spinal cord • preserve nerve function of baby • prevent infection of the exposed nerves and other tissues.

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