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Effects of SM Treatment on Body Weight Growth in Ovariectomized Rats

This study analyzes changes in body weight growth in rats following ovariectomy (OVX) and SM treatment. Results show significantly higher body weight growth in OVX groups compared to Sham group since the 2nd week post-OVX. Drug administration had no impact on this growth pattern. The study includes Sham, OVX-control, and 1SM, 3SM, 10SM, and 30SM groups. Each group had 7-10 rats.

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Effects of SM Treatment on Body Weight Growth in Ovariectomized Rats

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  1. 1st 2nd 3rd 4th 5th 6th 7th 8th 9th baseline Week Additional file 3 Note: P < 0.05~0.001 vs Sham group (from 2nd week). Additional file 3Changes in body weight growth in rats. From the second week after OVX, the rat’s body weight growth was significantly greater in ovariectomized groups (including OVX and all drug administration groups) than that in the Sham group. Drug administration did not affect the body weight growth pattern. Note: Rat groups include sham-operated (Sham), OVX-control (OVX), and 1, 3, 10 and 30 mg/kg SM-treated (1SM, 3SM, 10SM and 30SM) ovariectomized groups, total 6 groups (N = 7~10/each group).

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