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1. Structure of DNA

Section12.2. 1. Structure of DNA. Components of DNA. DNA (deoxyribonucleic acid) is a nucleic acid made up of nucleotides joined into long strands by covalent bonds. Nucleotides. Nucleotides are building blocks of nucleic acids Nucleotides: 3 parts 5-carbon sugar: deoxyribose

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1. Structure of DNA

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  1. Section12.2 1. Structure of DNA

  2. Components of DNA • DNA (deoxyribonucleic acid) is a nucleic acid made up of nucleotides joined into long strands by covalent bonds

  3. Nucleotides • Nucleotides are building blocks of nucleic acids • Nucleotides: 3 parts • 5-carbon sugar: deoxyribose • Phosphate group • Nitrogenous base • 4 Nitrogenous bases (contain Nitrogen): • Adenine • Guanine • Thymine • Cytosine

  4. Bonds • Nucleotides joined by covalent bonds • Forms between sugar of one nucleotide and phosphate group of the next. Nitrogenous bases -Stick out sideways from the nucleotide chain -Nucleotides can be joined together in a number of different ways -Any base sequence is possible -That’s what makes us so different! -Have a special chemical structure that is especially good at absorbing UV light

  5. Stop and Write(2-5 min.) • 1. What are the 3 components of a nucleotide? • 2. What are the four nitrogenous bases? • 3. Do you think excessive UV light could damage your DNA? How?

  6. Erwin Chargaff • Austrian-American biochemist • Discovered that % of: • Adenine [A]= Thymine [T] • Guanine[G]= Cytosine [C] P. 345 Analyzing data #1-4 (5 min.)

  7. 2. Double- helix • Explains Chargaff’s rule • Antiparallel strands • DNA runs in opposite directions Hydrogen bonds -Both strands of DNA are held together by H bonds between nitrogenous bases (A and T) and (G and C). -Base pairing -A always lines up perfectly with T -G always lines up perfectly with C

  8. Structure Review

  9. Photo credits • http://www.google.com/imgres?imgurl=http://katienelson4b.edublogs.org/files/2011/11/nucleotide-1p9gib5.jpg&imgrefurl=http://katienelson4b.edublogs.org/tag/nucleotide/&h=446&w=250&sz=75&tbnid=lfIfHbGruEmCDM:&tbnh=90&tbnw=50&prev=/search%3Fq%3Ddna%2Bnucleotides%26tbm%3Disch%26tbo%3Du&zoom=1&q=dna+nucleotides&usg=__lwz4o6W-xrLEn1zPP2NlGTfu7n0=&docid=_Box7VZ7RoXcCM&hl=en&sa=X&ei=KbChUNq2JJTAyQG9voDwBA&sqi=2&ved=0CDMQ9QEwAg&dur=6797 • http://4.bp.blogspot.com/-blHHFOAeRHw/Tbcr4yajYgI/AAAAAAAABTk/wQ9OpgOLhrA/s1600/Rosalind%2BFranklin%2B.jpg • http://lebbeuswoods.files.wordpress.com/2010/08/watson-crick-2.jpg

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