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Epidemiologic Basis of Tuberculosis Control Slides from the web site tbrieder

Epidemiologic Basis of Tuberculosis Control Slides from the web site http://www.tbrieder.org Compiled by: Hans L Rieder. The five core modules of The Union’s International Tuberculosis Courses. The DOTS Strategy of the national tuberculosis program. Intervention strategies. Etiologic

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Epidemiologic Basis of Tuberculosis Control Slides from the web site tbrieder

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  1. Epidemiologic Basis of Tuberculosis Control Slides from the web site http://www.tbrieder.org Compiled by: Hans L Rieder

  2. The five core modules of The Union’s International Tuberculosis Courses The DOTS Strategy of the national tuberculosis program Intervention strategies Etiologic agent Individual Community Bacteriologic basis Clinical presentation Epidemiologic basis

  3. A Model for the Epidemiology of Tuberculosis Risk Risk Risk Risk factors factors factors factors Infectious tuberculosis Subclinical Death Exposure infection Non-infectious tuberculosis Rieder HL. Infection 1995;23:1-4

  4. Exposure to M. tuberculosis o Etiologic epidemiology o Descriptive epidemiology o Predictive epidemiology

  5. Infection with M. tuberculosis o Etiologic epidemiology o Descriptive epidemiology o Predictive epidemiology

  6. Risk of Infection Given Exposure: Largely Exogenous Factors Particles Volume x Exposure time Particles: Volume: Exposure time: Production of infectious droplet nuclei Volume of air and ventilation Time of inhaling air with droplet nuclei

  7. Production of Infectious Droplets and Droplet Nuclei o Aerosolization o Site and form of disease

  8. Clearance of Air o Dispersion of bacilli o Survival of bacilli

  9. Risk of Infection Among Contacts as a Function of Exposure Duration

  10. Infection with M. tuberculosis o Etiologic epidemiology o Descriptive epidemiology o Predictive epidemiology

  11. Descriptive epidemiology of tuberculous infection o Methodological issues in determining prevalence of tuberculous infection o Prevalence of tuberculous infection

  12. Standardization of the Tuberculin Skin Test o Standardization of tuberculin o Standardization of administration o Standardization of reading

  13. Original PPD-S Produced by Florence Seibert No. 23 No. 24 Picture courtesy: Brennan MJ, Anderson C, Quander J. United States Food and Drug Administration, November 29, 2001

  14. Mantoux C. La Presse Médicale 1910;2:10-15

  15. Sensitivity to M. intracellulare in the United States Edwards LB, et al. Am Rev Respir Dis 1969;(No 4, part 2):13

  16. The Litmus Test: Case Incidence Given a Test Result

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