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HEART TRANSPLANTATION

HEART TRANSPLANTATION. Pediatric Recipients. ISHLT. 2008. J Heart Lung Transplant 2008;27: 937-983. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS (Transplants: January 1996 - June 2007). Number of Transplants. ISHLT. 2008. J Heart Lung Transplant 2008;27: 937-983.

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HEART TRANSPLANTATION

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  1. HEART TRANSPLANTATION Pediatric Recipients ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  2. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2007) Number of Transplants ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  3. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART RECIPIENTS(Transplants: January 1996 - June 2007) Number of Transplants ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  4. AGE DISTRIBUTION OF PEDIATRIC HEART RECIPIENTSBy Year of Transplant Number of Transplants NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of hearts transplanted worldwide has increased and/or decreased in recent years. ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  5. NUMBER OF CENTERS REPORTING PEDIATRIC HEART TRANSPLANTS Number of Pediatric Cases Reporting ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  6. AVERAGE CENTER VOLUMEPediatric Heart Transplants: January 1, 1997 - June 30, 2007 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  7. DISTRIBUTION OF TRANSPLANTS BY CENTER VOLUMEPediatric Heart Transplants: January 1, 1997 - June 30, 2007 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  8. PEDIATRIC HEART RE-TRANSPLANTSBy Transplant YearRetransplants: January 1994 – December 2006 Year of transplant ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  9. PEDIATRIC HEART RE-TRANSPLANTSBy Intertransplant IntervalRetransplants: January 1994 - June 2007 Time Between Previous and Current Transplant ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  10. KAPLAN-MEIER SURVIVAL RATES FOR PEDIATRIC HEART RETRANSPLANTS STRATIFIED BY INTER-TRANSPLANT INTERVALRetransplants: January 1994 - June 2006 Time (years) since most recent transplant ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  11. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: < 1 Year) 1988-1995 1/1996-6/2007 % of Cases ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  12. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 1-10 Years) 1988-1995 1/1996-6/2007 % of Cases ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  13. DIAGNOSIS IN PEDIATRIC HEART TRANSPLANT RECIPIENTS (Age: 11-17 Years) 1988-1995 1/1996-6/2007 % of Cases ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  14. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival(Transplants: 1/1982-6/2006) Survival (%) ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  15. PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival (Transplants: 1/1982-6/2006) Survival (%) ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  16. PEDIATRIC HEART TRANSPLANTATIONConditional Kaplan-Meier Survival for Recent Era (Transplants: 1/1999-6/2006) Survival (%) ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  17. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era(Transplants: 1/1982-6/2006) Survival (%) ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  18. PEDIATRIC HEART TRANSPLANTATION Kaplan-Meier Survival by Era (Transplants: 1/1982-6/2005)Age: < 1 Year Survival (%) ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  19. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (Transplants: 1/1982-6/2005)Age: 1-10 Years Survival (%) ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  20. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Era (Transplants: 1/1982-6/2005)Age: 11-17 Years Survival (%) ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  21. PEDIATRIC HEART TRANSPLANTS:AVERAGE CENTER VOLUME DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2007 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  22. PEDIATRIC HEART TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2007 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  23. PEDIATRIC HEART TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATION Transplants between January 2000 and June 2007 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  24. PEDIATRIC HEART TRANSPLANTS:DONOR AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2007 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  25. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Risk Factors For 1 Year Mortality N=3,395 ISHLT 2008 Reference diagnosis = cardiomyopathy J Heart Lung Transplant 2008;27: 937-983

  26. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2005)Borderline Significant Risk Factors For 1 Year Mortality N=3,395 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  27. PEDIATRIC HEART TRANSPLANTS(1/1995-6/2006)Risk Factors for 1 Year Mortality N=3,395 ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  28. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Risk Factors for 1 Year MortalityRecipient Age ISHLT 2008 N=3,395 J Heart Lung Transplant 2008;27: 937-983

  29. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Risk Factors for 1 Year MortalityDonor Age ISHLT 2008 N=3,395 J Heart Lung Transplant 2008;27: 937-983

  30. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Risk Factors for 1 Year MortalityPre-TransplantCreatinine ISHLT 2008 N=3,395 J Heart Lung Transplant 2008;27: 937-983

  31. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Risk Factors for 1 Year MortalityCenter Volume for Pediatric Transplants ISHLT 2008 N=3,395 J Heart Lung Transplant 2008;27: 937-983

  32. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Risk Factors for 1 Year MortalityDonor BSA ISHLT 2008 N=3,395 J Heart Lung Transplant 2008;27: 937-983

  33. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2006)Factors Not Significant for 1 Year Mortality Recipient Factors: IV inotropes, sternotomy, history of malignancy, hospitalized, diabetes Donor Factors: Gender, clinical infection, history of diabetes Transplant Factors: CMV mismatch, ischemia time, HLA mismatch ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  34. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1997)Risk Factors For 10 Year Mortality ISHLT N=697 2008 J Heart Lung Transplant 2008;27: 937-983

  35. PEDIATRIC HEART TRANSPLANTS(1/1995-6/1997)Risk Factors for 10 Year Mortality ISHLT N=697 2008 J Heart Lung Transplant 2008;27: 937-983

  36. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1997)Risk Factors for 10 Year MortalityPre-Transplant Creatinine ISHLT N=697 2008 J Heart Lung Transplant 2008;27: 937-983

  37. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1997)Risk Factors for 10 Year Mortality Donor Weight ISHLT 2008 N=697 J Heart Lung Transplant 2008;27: 937-983

  38. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1997)Risk Factors for 10 Year MortalityCenter Volume for Pediatric Transplants ISHLT N=697 2008 J Heart Lung Transplant 2008;27: 937-983

  39. PEDIATRIC HEART TRANSPLANTS (1/1995-6/1997)Risk Factors for 10 Year MortalityBSA Ratio (Donor BSA/Recipient BSA) ISHLT N=697 2008 J Heart Lung Transplant 2008;27: 937-983

  40. PEDIATRIC HEART TRANSPLANTS (1/1995-6/2000)Factors Not Significant for 10 Year Mortality Recipient Factors: PRA, diabetes, repeat transplant, transfusions, hospitalized, gender, PGE, VAD, bilirubin Donor Factors: Cause of death, age, clinical infection Transplant Factors: Ischemia time, HLA mismatch, CMV mismatch ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  41. PEDIATRIC HEART RECIPIENTSFunctional Status of Surviving Recipients(Follow-ups: April 1994 - June 2007) ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  42. PEDIATRIC HEART RECIPIENTS Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2007) ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  43. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression(Transplants: January 2001 - June 2007) % of Patients ISHLT 2008 Analysis is limited to patients who were alive at the time of the follow-up J Heart Lung Transplant 2008;27: 937-983

  44. PEDIATRIC HEART RECIPIENTSInduction Immunosuppression (Transplants: January 2001 - June 2007) Test of increasing trend over time: Any induction p < 0.0001 Polyclonal p < 0.0001 IL2 p = 0.0029 ISHLT 2008 Analysis is limited to patients who were alive at the time of the follow-up J Heart Lung Transplant 2008;27: 937-983

  45. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Induction Group (Transplants: January 2000 – June 2005) Conditional on Survival to 14 Days No comparisons were statistically significant. Survival (%) ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  46. PEDIATRIC HEART TRANSPLANTATION Kaplan-Meier Survival by Induction Group and Rejection Between Transplant Discharge and 1-Year Follow-up (1-Year Follow-ups: July 2004 - June 2006) Conditional on Survival to 1 Year Survival (%) No pair-wise comparisons of survival by induction were statistically significant within either rejection grouping except No induction/Rejection vs. Polyclonal/Rejection (p=0.0329). ISHLT 2008 J Heart Lung Transplant 2008;27: 937-983

  47. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Induction Group (Transplants: January 2000 – June 2005)Conditional on Survival to 14 DaysAge: < 1 Year Survival (%) ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  48. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Induction Group (Transplants: January 2000 – June 2005) Conditional on Survival to 14 DaysAge: 1-10 Years Survival (%) No comparisons were statistically significant. ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  49. PEDIATRIC HEART TRANSPLANTATIONKaplan-Meier Survival by Induction Group (Transplants: January 2000 – June 2005)Conditional on Survival to 14 DaysAge: 11-17 Years Survival (%) ISHLT 2008 Last updated based on data as of December 2006 J Heart Lung Transplant 2008;27: 937-983

  50. PEDIATRIC HEART RECIPIENTSMaintenance Immunosuppression at Time of Follow-up(Follow-ups: January 2001 - June 2007) % of Patients NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2008 Analysis is limited to patients who were alive at the time of the follow-up J Heart Lung Transplant 2008;27: 937-983

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