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Cytopathology Challenge! Weekly Cases

Cytopathology Challenge! Weekly Cases

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Cytopathology Challenge! Weekly Cases

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  1. Cytopathology Challenge! Weekly Cases October 22th 2007 Pap Smear Special Edition!

  2. 24 year old female. ThinPrep pap • Trichomonas • Lactobacillus • Gonorrhea • Bacterial Vaginosis • Artifact 1

  3. 34 year old female. ThinPrep pap • Reactive endocervical cells • Squamous metaplasia • ASCUS • LSIL • HSIL 2

  4. 34 year old female. ThinPrep pap • Endocervical cells • HSIL • Endometrial cells • Squamous metaplasia • Lymphocytes 3

  5. 29 year old female. ThinPrep pap • Squamous metaplasia • Reactive endocervical cells • ASC-US • LSIL • HSIL 4

  6. 24 year old female. ThinPrep pap • Trichomonas • Lactobacillus • Gonorrhea • Bacterial Vaginosis • Artifact 5

  7. 29 year old female. ThinPrep pap • Squamous metaplasia • Reactive endocervical cells • ASC-US • LSIL • HSIL 6

  8. 29 year old female. ThinPrep pap • Squamous metaplasia • Reactive endocervical cells • ASC-US • LSIL • HSIL 7

  9. 29 year old female. ThinPrep pap • Reactive • Endocervical cells • ASC-US • LSIL • HSIL 8

  10. 34 year old female. ThinPrep pap A. Squamous metaplasia B. Reactive endocervical cells C. ASC-US D. LSIL E. HSIL 9

  11. 34 year old female. ThinPrep pap • Contaminant from a BAL • HSIL • Endometrial cells • Adenocarcinoma • Tubal metaplasia 10

  12. Answers • D Bacterial Vaginosis • Clue cells with cocci on them • D LSIL • Koilocytes! • C Endocervical cells • Honeycomb, regular, not dysplastic • E HSIL • High NC ratio, irregular nuclei • B Lactobacillus • Rods on the cells • D LSIL • Koilocytes again! • A Squamous Metaplasia • Can look like HSIL, but nuclei not so big and still regular in contour. • A Reactive • See the trichomonas hiding in there…… • E. HSIL • High NC ratio, irregular nuclei • E Tubal metaplasia • Ciliated cells in a pap smear can be metaplastic ciliated metaplasia.