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Students will be able to:. explain what is meant by “genetic linkage” understand the meaning of parental and recombinant types from testcross data: deduce whether two genes are likely to be linked identify parental and recombinant classes. 5.
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Students will be able to: • explain what is meant by “genetic linkage” • understand the meaning of parental and recombinant types • from testcross data: • deduce whether two genes are likely to be linked • identify parental and recombinant classes
5 The American Journal of Human Genetics 82, 150–159, January 2008 3 4 1 2
w+ m+ w- m- X In the testcross below, what fraction of flies will be white-eyed, long winged? w+ m+ w- m- white eyes short wings red eyes long wings w- m- w+ m+ X w- m- w- m- white, short red, long A. 3/4 B. ¼ C. ½. D. 0 white, long
If w and m are located near each other on the chromosome, how will that change the proportion? w+ w- m- m+ X w+ w- m+ m- white eyes short wings red eyes long wings w+ w- m- m+ X w- w- m- m- white, short red, long ? white, long
Identify parental and recombinant classes CC shsh cc ShSh X colored, shrunken white, plump Cc Shsh cc shsh X colored, plump white, shrunken colored plump white shrunken
What are the parental/recombinant genotypes? X CC shsh cc ShSh colored, shrunken white, plump X Cc Shsh cc shsh colored, plump white, shrunken