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Accomplishments and Future Plans of Dr. Zinhle Makatini's Laboratory Operational Team

Over the past year, Dr. Zinhle Makatini and the Laboratory Operational Team achieved significant milestones, including initiating a contract with Lancet Lab for essential services like CD4 and HIV RNA testing and establishing comprehensive lab procedures. Personnel training at Mil and Mtubatuba was also prioritized. Looking ahead, the team will evaluate its composition, transition funding management to SAIC, and enhance laboratory capabilities, ensuring effective communication for the success of Project Phidisa in the coming year.

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Accomplishments and Future Plans of Dr. Zinhle Makatini's Laboratory Operational Team

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  1. Laboratory Operational Team Dr Zinhle Makatini

  2. Accomplishments over the past year • Initiated contract with Lancet Lab for: • CD4, HIV RNA, • routine safety labs, • repository lab and sample transport • Established procedures for: - Phlebotomy (pre- and post-test counselling) - HIV and pregnancy rapid testing - Blood smears - Sample processing and shipping • Trained lab personnel at 1 Mil and Mtubatuba

  3. Tasks for Upcoming Year • Evaluate composition of Laboratory Team • Develop transition strategy for funding Lancet Contract • Re-evaluate opportunity for development of enhanced laboratory capability within SAMHS – beginning with sample repository

  4. Composition of Laboratory Team • Current Members of Lab Operational Team: South Africa USA • Dr Z Makatini (Chair) Dr Robin Dewar (Mentor) • Dr MJ Mphahlele Ms Julie Metcalf - Dr L Webber Ms Helene Highbarger • Phidisa Lab Staff: - Director (1) - Deputy Director (1) - vacant - Lab assistants (12) – 8 vacant

  5. Transition Strategy for Funding Lancet Contract • Current Status – HJF administers funding of the Lancet contract • Preparation for change – Scientific Application International Corporation (SAIC) to administer funding for the Lancet • Transition from HJF to SAIC projected to take 3-4 months • Line of communication for Lancet Laboratory will continue to go through the Phidisa Laboratory Director Dr Z Makatini

  6. Lab Infrastructure at SAMHS • Creation of a repository within the SAMHS is the next most important task. Requirements - Building permits - Operational - Facility - Personnel - Data base

  7. Lab Research Proposals • Discordant couples • HIV Genotyping • Predictive value of lab markers: • Hemoglobin • Total lymphocyte count • Weight

  8. Phidisa Laboratory Budget for Fiscal Year ending June 2005* Clinic Labs SAR 350,000 Site visits SAR 70,000 Meetings SAR 45,000 Lancet contract SAR 10,250,000 Repository SAR 7,000,000 *Does not include personnel & genotyping costs

  9. Laboratory Requests for: Operational Teams Please work with the Lab Director to: - Identify lab-dedicated staff. - Establish the patient flow scheme for each site. - Train clinical staff on laboratory specific issues.

  10. Concluding Remarks • With the upcoming implementation of new protocols and the opening of new sites, we anticipate a busy year for all, including the Site Labs. • Good communication between the site PIs and the Lab Director will ensure the continued success of Project Phidisa.

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