Thyroid Cytopathology Unknown Cases For Discussion Syed Z. Ali, M.D. The Johns Hopkins Hospital, Baltimore, Maryland
Case 1 • A 46 year-old woman with a 3.2 cm solid, left thyroid nodule present for • 2 years. There has been a recent increase in the size of the nodule. Family • history is positive for papillary thyroid carcinoma in the mother, who is alive • and free of disease. • Ultrasound-guided FNA. Smears stained with Diff-Quik stain.
Case 2 • A 55 year-old man with a 3.0 cm solid, right thyroid nodule present for • less than 3 months. The nodule shows coarse calcifications, which radiographically, • are thought to be suspicious for papillary thyroid carcinoma. • Ultrasound-guided FNA. A flow cytometry was ordered after on-site evaluation. • Smears stained with Diff-Quik and Papanicolaou stains.
Case 3 • A 62 year-old woman presents with a 1.2 cm left lobe thyroid nodule. • Past medical history reveals a cavernous sinus meningioma 17 years ago • treated with subtotal resection and external beam radiation therapy. The • thyroid nodule was discovered incidentally on routine imaging studies. The • nodule was noted to have a hypoechoic rim and small, punctate, echogenic • foci that were suggestive of microcalcifications. • Ultrasound-guided FNA. Smears stained with Diff-Quik and Papanicolaou stains.
Case 4 • A 28 year-old woman with an incidentally discovered 1.8 cm solid, left thyroid • nodule. She complains of bone pain, worsening fatigue and lethargy. • Ultrasound-guided FNA. Smears stained with Diff-Quik and Papanicolaou stains.
Case 5 • A 61 yr-old man was evaluated for a slow-growing left thyroid mass that was • present for 2 yr despite thyroid hormone suppression. Thyroid-stimulating • hormone (TSH) was within normal limits. Past history was significant for • radium treatment of his adenoid at age 6. • Ultrasound-guided FNA. Smears stained with Diff-Quik and Papanicolaou stains.