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Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045

Mercaptopropyl-Modified Mesoporous Silica: A Remarkable Support for the Preparation of a Reusable, Heterogeneous Palladium Catalyst for Coupling Reactions. Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045. Palladium-Catalyzed Reactions.

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Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045

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  1. Mercaptopropyl-Modified Mesoporous Silica: A Remarkable Support for the Preparation of a Reusable, Heterogeneous Palladium Catalyst for Coupling Reactions Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045

  2. Palladium-Catalyzed Reactions

  3. Z=COOR, Ph X=Cl, Br, I Suzuki-Reaction X=Cl, Br, I Heck Reaction

  4. www.bgu.ac.il/mesoporous/ html/kinetics.htm

  5. 為何使用SBA-15作為載體 • 具多孔性 • 高表面積 • 表面的silanol密度高，有利(CH3O)3Si(CH2)3SH 與silica表面進行縮合反應

  6. Pd(OAc)2 in THF Treated with Various Scavengers

  7. Scavenging of Pd with SBA-15-SH and SiO2-SH

  8. Suzuki-Miyaura Couplings with SBA-SH-Pd

  9. Substrate Scope for the Suzuki-Miyaura Coupling

  10. Reusability of the Catalyst in the Suzuki-Miyaura Reaction

  11. SBA-15-Modified Pd Catalysts for the Mizoroki-Heck Reaction

  12. Hot Filtration Test

  13. Three-Phase Test in the Suzuki-Miyaura Reaction

  14. Conclusions • Thiol-functionalized mesoporous silicates are efficient Pd scavengers and this materials have high ability of catalysis for Heck and Suzuki reaction. • Several heterogeneity tests were indicate that the majority of the catalysis (>95%) occurs on the support via a truly heterogeneous catalyst.

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