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Understanding Stress and Heart Disease: Models and Risk Factors

Explore psychological risk factors for coronary artery disease (CAD) and cardiovascular disease (CVD) through heuristic models. Learn about stress, inflammation, and CVD from a physiological standpoint. Stay updated on the latest research in stress and heart disease, including the impact of psychological stress on platelet activation and clotting. Discover the processes of atheroma, atherosclerosis, plaque rupture, and myocardial infarction to gain insights into managing psychosocial risk factors in cardiac practice. This comprehensive guide offers a blend of psychological and physiological perspectives to enhance your understanding of the intricate relationship between stress and heart health.

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Understanding Stress and Heart Disease: Models and Risk Factors

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  1. Stress and heart disease: a few basics and heuristic models

  2. Kop provides a readable account of psychological risk factors for CAD. His model provides a useful way of organising the material on stress and CVD & the material on “vital exhaustion” will be covered later in the lecture on depression. Kop, WJ (1999) Chronic and acute psychological risk factors for clinical manifestations of coronary artery disease. Psychosomatic Medicine, 61, 476-487. Black and Garbutt are not for the feint hearted. They offer a very complex physiological model of stress, inflammation and CVD. Incorporates a lot of important new information but only for those with background in biology. I shall use model illustratively Black, PH., & Garbutt, LD (2002). Stress, inflammation and cardiovascular disease. J. of Psychosomatic Res., 52, 1-23

  3. Rozanski paper is very up to date account of stress and heart disease written for cardiologists. I strongly recommend it. Rozanski, A., Blumenthal, JA., Davidson, KW, Saab, PC., Kubzansky, L (2005). The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice. J. American College of Cardiology., 45, 637-651.

  4. Words you main not have come across Atheroma, Atherosclerosis, Atherosclerotic plaque Thrombus

  5. Process of build up of atherosclerotic plaque, plaque rupture and thrombus formation.

  6. No MI, plaque remains Unstable situation Artery blocked, MI results What causes a Myocardial Infarction: Plaque rupture and blocked coronary artery

  7. Black PH Garbutt LD (2003) Stress, inflammation and cardiovascular disease, J Psychosom. Res 52, 1 -23

  8. Psychological stress and platelet activation: Differences in platelet reactivity in healthy men during active and passive stressors. Patterson, S. M.; Zakowski, SG.; Hall, Martica H.; Health Psychology, Vol 13, 1994. pp. 34-38.

  9. Effects of stress on platelets, and hence clotting & process of atherogenesis. See particularly PF (Platelet Factor) 4

  10. The diathesis model: stress plus vulnerability

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