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Danish National Birth Cohort (DNBC) dnbc.dk

www.club11.dk. SPECIMEN. COLLECTED ( yes/no). Maternal. None. Baby/Child. None. Cancer Cases. Ascertainment of Cancer cases: Danish National Patient Registry, August 2008 Number of Cancer Cases Total: 185 Leukemia: 62 - ALL 33 cases (%) - AML 3 cases(%)

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Danish National Birth Cohort (DNBC) dnbc.dk

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  1. www.club11.dk SPECIMEN COLLECTED ( yes/no) Maternal None Baby/Child None Cancer Cases Ascertainment of Cancer cases: Danish National Patient Registry, August 2008 Number of Cancer Cases Total: 185 Leukemia: 62 - ALL 33 cases (%) - AML 3 cases(%) Brain: 29 cases (%) Others: n (%) Acknowledgements DNBC Management Dr. Jørn Olsen Dr. Mads Melbye Dr. Thorkild IA Sørensen Dr. Anne-Marie Nybo Andersen Dr. Sjurdur F. Olsen Dr. Peter Aaby Danish National Birth Cohort (DNBC) www.dnbc.dk Jørn Olsen, UCLA & Aarhus University, Denmark Biospecimens Population sample Exposure domains in questionnaires SPECIMENS COLLECTED ( yes/no) Years of recruitment: 1996-2002 Sampling method: All pregnant women in Denmark during the recruitment period. Approx. 60% of all pregnant women were invited and approx. 30% of the invited enlisted. Participants had to live in Denmark and speak Danish well enough to be able to complete telephone interviews. Response rate: Differs for the diff. collection waves but is between 93% and 60%. Number of live births at baseline: 96,841 Maternal • Prenatal Blood Yes Other: None • At birth Cord blood Yes Baby/Child • First year of life Blood Not in cohort, but may be obtained from national biobank Research Questions and Primary Outcomes • Population sample • Identifying prenatal and perinatal determinants of importance for reproductive failiures and diseases that manifest themselves later in life. • Main exposures of interest are: Lifestyle factors, diet, social conditions, infections, drugs & environmental exposures. Environmental Samples Methods and Data collection ”The Danish National Research Foundation has established the Danish Epidemiology Science Centre that initiated and created the Danish National Birth Cohort. The cohort is furthermore a result of a major grant from this Foundation. Additional support for the Danish National Birth Cohort is obtained from the Pharmacy Foundation, the Egmont Foundation, the March of Dimes Birth Defects Foundation, the Augustinus Foundation, and the Health Foundation” The DNBC 11-year follow-up started in June 2010. Approx. 22.000 records - 50% response rate in September 2011. I4C_Lyon 2009

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