1 / 6

Understanding Growth Hormone (GH) and Its Effects on Growth and Health

Discover the role of Growth Hormone (GH) in height increase, bone mineralization, muscle mass, and organ growth. Learn about conditions like Gigantism and Pituitary Tumor and how GH levels impact health.

erica-monroe
Télécharger la présentation

Understanding Growth Hormone (GH) and Its Effects on Growth and Health

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Growth Hormone (GH) Holly Farris

  2. What Is It? • 191-amino acid, single chained polypeptide • Synthesized, stored, and secreted by somatotrophic cells • Anterior Pituitary gland

  3. Function • Increased height in childhood and adolescents –most known effect • Increases mineralization of bones • Muscle mass • Stimulates growth of internal organs- excluding the brain • Immune system

  4. Positive or Negative? • Negative • High blood levels of IGF-I leads to decreased secretion of GH • IGF-1 directly suppresses the somatotrophic cells

  5. Hyper • Gigantism- excessive growth, usually in childhood • Most common • Pituitary Tumor - causes headaches, impair vision by pressure on the optic nerves

  6. Hypo • In children: • Growth failure • Short stature • In adults: • Increase in fat mass • Decrease muscle mass, energy and quality of life

More Related