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Randomness Testing in DNA Samples

This project investigates the randomness of DNA sequences derived from various genome sequencing projects. Utilizing computational tools like R and MATLAB, we apply mathematical tests to explore patterns and unique properties within the DNA sequences. The DNA samples are sourced from the Virtual Library of Genetics, focusing on the amelogenin gene (AMELY and AMELX) which is gender-specific. The study aims to discern differences in relative frequencies among sequences, enhancing our understanding of synthetic life and gender variance.

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Randomness Testing in DNA Samples

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  1. Randomness Testing in DNA Samples Laura Jean Champagne Advisor: Gary Davis

  2. Abstract • This project examines the randomization of DNA sequences based on current genome sequencing projects. Using computational programs, mainly R and MATLAB, different mathematical tests for randomness are applied to DNA sequences in an attempt to find patterns or other unique properties. DNA sequences used are obtained from the Virtual Library of Genetics.

  3. AMELY & AMELX • Amelogenin (tooth enamel protein) • Gender Specific

  4. Data – GenBank

  5. Data

  6. Correlagram

  7. Correlagram AMELX AMELY

  8. DNA Sequences

  9. Histogram AMELX AMELY

  10. Histogram of Amino Acids AMELX AMELY

  11. Why Bother? • Synthetic life • Gender differences

  12. Goals • Relative Frequency

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