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MethStatusBrowser -- Tutorial

This tutorial provides a detailed guide on using the MethStatusBrowser software for efficient analysis of methylation data. It covers key functionalities including data importing, peak attaching, and sample comparison, helping users understand how to effectively search, sort, and export comparison results. It also outlines necessary future enhancements, such as sample normalization and data pre-processing. Users will learn to identify significant differences between experimental and control groups and recognize valid and invalid signals in the dataset.

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MethStatusBrowser -- Tutorial

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  1. MethStatusBrowser -- Tutorial 钱自亮：zlqian@sibs.ac.cn 葛东亚：dyge@sibs.ac.cn

  2. Main Interface

  3. Outline • Data Importing • Peak Attaching • Sample Comparison • Comparison result searching/sorting • Results exporting • TODO

  4. Loading Samples into Software

  5. P-value setting

  6. Peak Attaching

  7. Sample Comparison

  8. DiffScore indicating the difference between experiment group and control group Black cell indicating piece methyalted in this region Red cell indicating invalid signal readout

  9. Experiment Group Control Group

  10. Comparison Result Searching

  11. Comparison Result Sorting Mouse click table header “DiffScore”

  12. Table Data Exporting

  13. Image Exporting

  14. TODO • To implement data pre-processing • Array design • Sample normalization • Masking invalid probe/piece • Bug fixing

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