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CITR Annual Report Exhibits

CITR Annual Report Exhibits

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CITR Annual Report Exhibits

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  1. CITR Annual Report Exhibits 2007 CITR Annual ReportExhibitsPrepared by:CITR Coordinating CenterThe EMMES CorporationRockville, MDSponsored by:National Institute of Diabetes & Digestive & Kidney DiseasesNational Institutes of HealthBethesda, MDDatafile Closure: April 1, 2007

  2. Chapter 1: Islet Transplant Activity Chapter 2: Recipient and Donor Characteristics Chapter 3: Pancreas Procurement, Islet Processing and Infusion Characteristics Chapter 4: Immunosuppression and Other Medications Chapter 5: Graft Function Chapter 6: Liver, Kidney, Lipid and PRA Effects Chapter 7: Adverse Events Chapter 8: Registry Data Quality Review CITR Coordinating Center CITR Committees Table of Contents

  3. Chapter 1: Islet Transplant Activity

  4. Islet Transplant Centers Reporting Data to CITR:Participating North American Centers 1999-2006 A - CITR Centers with at least one islet allograft infusion procedure conducted in 2006C - CITR Centers with no islet allograft infusions in 2006D - CITR Coordinating Center

  5. Number of Islet Transplantation Centers Performing Islet Allografts per Year and Number with Data Entered in CITR Database All North American Islet Transplant Centers 1999-2006

  6. Total Number of Islet Transplant Recipients, Recipients at CITR-Participating Centers, and Recipients with Detailed Data Reported to CITR By Year of First Islet Allograft InfusionAll North American Islet Transplant Centers 1999-2006 The Islet Transplant Summary (ITS) questionnaire is completed by all North American Islet Transplant Programs regardless of their participation in the Registry. Of 45 North American islet transplant programs polled, all have provided this information through 2006.

  7. Total Number of Islet Allograft Infusion Procedures Performed and Number with Data Reported to CITR:CITR-Participating North American Islet Transplant Centers 1999-2006

  8. Total Number (N=579) of Islet Allograft Infusion Procedures Conducted and Entered in CITR Database, by Year and Infusion Procedure Number:CITR-Participating North American and International Centers, 1999-2006

  9. Total Number (N=579) of Islet Allograft Infusion Procedures Per Recipient:CITR-Participating North American and International Centers, 1999-2006

  10. Islet Alone and Islet After Kidney Recipients:CITR-Participating North American and International Centers, 1999-2006

  11. Chapter 2: Recipient and Donor Characteristics

  12. Recipient Demographics

  13. Transplant Recipient Primary Funding InformationCITR-Participating US Centers

  14. Recipient Characteristics at First Infusion

  15. Recipient Diabetes Characteristics at First Infusion

  16. Recipient Diabetes Characteristics at First Infusion(continued)

  17. Recipient Infectious Disease Testing at First Infusion

  18. Recipient Characteristics at First Infusion by Total Number of Infusions Received

  19. Recipient Demographics and Characteristics at First Infusionby Total Number of Infusions Received

  20. Recipient Laboratory Values at First Infusion

  21. Donor DemographicsAll Allograft Donors

  22. Donor CharacteristicsAll Allograft Donors

  23. Donor CharacteristicsAll Allograft Donors(continued)

  24. Characteristics of Organ Procurement and Donor Cause of DeathAll Allograft Donors

  25. Treatments Given to Donor During HospitalizationAll Allograft Donors

  26. Treatments Given to Donor During HospitalizationAll Allograft Donors(continued)

  27. Donor SerologyAll Allograft Donors

  28. Donor Laboratory DataAll Allograft Donors

  29. Organ Crossmatch ResultsAll Allograft Donors

  30. Chapter 3: Pancreas Procurement, Islet Processing and Infusion Characteristics

  31. Pancreas Procurement and Islet Processing

  32. Pancreas Procurement and Islet Processing (continued)

  33. Pancreas Procurement and Islet Processing (continued)

  34. Cold Ischemia Information

  35. Islet Equivalents and Timing of Count

  36. Islet Product Characterization

  37. Islet Characteristics by Pancreas Preservation Method

  38. Correlation of Islet Characteristics with Donor, Recovery, and Processing Characteristics

  39. Islet Product and Infusion Characteristics by Infusion Sequence

  40. Mean Number of Islet Equivalents/Kg Recipient by Total Number of Infusions Received

  41. Pre Infusion Portal Pressure by Infusion Sequence

  42. Peak Portal Pressure by Infusion Sequence

  43. Closure Portal Pressure by Infusion Sequence

  44. Change from Pre Infusion to Closure Portal Pressure by Infusion Sequence

  45. Change from Pre Infusion to Peak Portal Pressure by Infusion Sequence

  46. Cell Volume Infused per Infusion by Infusion Year

  47. Chapter 4: Immunosuppression and Other Medications

  48. Immunosuppression Regimen at Time of First Infusion

  49. Immunosuppression Regimen at Time of First Infusion (continued)

  50. T Cell Antibodies Used During First Infusion for Induction Therapy