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Microfluidics Mixing Chamber

Microfluidics Mixing Chamber. Where? / With Whom? Intro to Project Proposal How?. Micro-Fabrication Facility (MFF) . Dr. Michael Khbeis Kristopher Lawler Andy Lingley. Class 10000 cleanroom -> Class 100 11,500 sq ft of wet & dry lab space Photolithography Nanolithography

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Microfluidics Mixing Chamber

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  1. Microfluidics Mixing Chamber

  2. Where? / With Whom? Intro to Project Proposal How?

  3. Micro-Fabrication Facility (MFF) • Dr. Michael Khbeis • Kristopher Lawler • Andy Lingley • Class 10000 cleanroom -> Class 100 • 11,500 sqft of wet & dry lab space • Photolithography • Nanolithography • Dry Etch • PVD • CVD • Thermal processing • Metrology

  4. How is microfluidic mixing different? Turbulent [5] Laminar

  5. Reynolds Number[2] • Re = (ρ * V * L) / mu • Dimensionless measure of the ratio of inertia force to viscous force • Inertial forces = density (ρ) * velocity (V) * gradient of the velocity (dV/dx) • Viscous forces = dynamic viscosity coefficient (μ) * second gradient of the velocity (d2V/dx2) • High Reynolds numbers - turbulent mixing • Low Reynolds numbers - mixing relies on diffusion • 0.1 = (1000kg/m3 * 0.0001m * 0.001m/s)[1] 0.001Ns/m2

  6. Passive Microfluidic Mixers[1] • Lamination • Intersecting Channels • Zigzag Channels • Three-Dimensional Serpentine Structures • Embedded Barriers • Slanted Wells • Surface-Chemistry Technology in Microchannels

  7. Laminar mixing [1] • Diffusion limited • Takes time and distance

  8. Intersecting and Zigzag Channels [1] [1]

  9. Three-Dimensional Serpentine Structures and Grooves [1]

  10. Embedded Barriers [4]

  11. Hong Chamber [6]

  12. Questions?

  13. [7]

  14. Works Cited Lee CY, Chang CL, Wang YN, Fu LM (2011) Microfluidic mixing: a review. Int J MolSci 12: 3263–3287. Benson, Tom. "Reynolds Number." Reynolds Number. NASA.gov, 22 May 2009. Web. 18 Apr. 2013. <http://www.grc.nasa.gov/WWW/K-12/airplane/reynolds.html>. De Buryn Kops, Steve, and Jim Riley. "Turbulent Mixing." EFluids Gallery Image and Description. EFluids.com, n.d. Web. 18 Apr. 2013. <http://www.efluids.com/efluids/gallery/gallery_pages/mixing_page.htm>. "Injection Molding Static Mixing Nozzle (Type SMN)." - StaMixCo Polymer Melt Viscous Processing Static Mixer Products & Technology. Stamixco-usa.com, n.d. Web. 18 Apr. 2013. <http://www.stamixco-usa.com/products/injection-molding-mixing-nozzle-and-filter/default.html>. "Mass Transport · Teaching Notes." Department of Chemical Engineering and Biotechnology. University of Cambridge, 2013. Web. 18 Apr. 2013. <http://www.ceb.cam.ac.uk/pages/mass-transport.html>. "Microfluidic CFD Applications: Multiphase Mixing and Bubble Dynamics." Microfluidics Applications: Simulating Multiphase Mixing. Flow Science, n.d. Web. 19 Apr. 2013. <http://www.flow3d.com/apps/microfluidics/multiphase-mixing.html>. Applied Physical Sciences - Chemistry: Andres W. Martinez, Scott T. Phillips, and George M. WhitesidesThree-dimensional microfluidic devices fabricated in layered paper and tape PNAS 2008 105 (50) 19606-19611; published ahead of print December 8, 2008, doi:10.1073/pnas.0810903105

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