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IUI A to Z. TYPICAL PREGNANCY RATE PER CYCLE WITH VARIOUS TREATMENT OPTIONS In Infertility. Effect of Etiology on Success Rate with IUI. Endometriosis,Tubal factor, severe male factor and combined factor should proceed earlier to higher level ART.
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TYPICAL PREGNANCY RATEPER CYCLE WITH VARIOUS TREATMENT OPTIONS In Infertility
Endometriosis,Tubal factor, severe male factor and combined factor should proceed earlier to higher level ART
Our IUI Experience(2009- 2011) N = 369 = 23.57% (two cycles) (world over success rate 10 to 15% only) • Idiopathic - 30% - (2 cycles) • PCOD – 30% - (r FSH) (2 cycles) • Cervical Factor 20% • Endometriosis – 15% • After treatment for TB 15% • Immunological cause TNF ↑ (treated ) 5 %
Male Infertility • 5 - 20 millions 15% • Less then 5 million Nil • AID – 46% (2 cycles)
Success rates according to AGE (Success rate in 1st 2 cycles) • Less then 30 – 28 % • Less then 35 – 22% • 35- 39 years - 8 % • 40 + Nil
PREREQUISITES • Age < 40 yrs • Spont. / Induced ovulation • One patent FT • >10 million pre wash semen count • >5 million post wash semen count • Easy access to uterine cavity
INTRAUTERINE INSEMINATION (IUI):Steps 1. Patients selection & workup 2. Ovarian stimulation 3. Semen wash 4. Insemination technique 5. Luteal support
EJACULATORY FAILURE • Severe hypospadias • Retro grade ejaculation • Paraplegics • Impotence & erectile dysfunction
Super ovulationV/sControl Ovarian Hyperstimulation • Stimulation • Monitoring • Follicle growth & release of multiple eggs
Complication of IUIStimulation , Technique & others - Infection -Rare - Multiple Pregnancy- OHSS