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Optimizing Intermediate Dose Regions in SBRT for Enhanced Tissue Protection

This discussion explores the significance of conformal high-dose and compact intermediate-dose regions in Stereotactic Body Radiation Therapy (SBRT). Emphasizing the importance of minimizing toxicity, it highlights the need for the intermediate dose region to be as compact as possible within normal tissues. The principle of delivering minimal dose to a large volume of normal tissue is examined, emphasizing its implications for structures such as the pulmonary veins, bronchus, lungs, esophagus, chest wall, spinal cord, and skin, all while respecting normal tissue constraints.

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Optimizing Intermediate Dose Regions in SBRT for Enhanced Tissue Protection

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Presentation Transcript

  1. Conformal high dose

  2. Compact intermediate dose The intermediate dose region is in normal tissues, accounts for toxicity, and should be made as compact as possible.

  3. Very large low dose volume SBRT assumption: A little dose to a lot of normal tissue is better than a lot of dose to a little normal tissue

  4. Pulmonary Vein Bronchus Lung Esophagus Chestwall Cord Skin Respect Normal Tissue Constraints

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