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Chromosome structure

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Chromosome structure. VINTAGE (about 1965). MALE (Much nicer) … but not a lot of detail. G-banding Also shows DNA profile markers. Let’s add some color. FISH’ing anyone?. F.I.S.H. Fluorescence In Situ Hybridization. F.I.S.H. Fluorescence In Situ Hybridization.

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Chromosome structure

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  1. Chromosome structure

  2. VINTAGE (about 1965)

  3. MALE (Much nicer)… but not a lot of detail

  4. G-bandingAlso shows DNA profile markers

  5. Let’s add some color

  6. FISH’ing anyone?

  7. F.I.S.H.Fluorescence In Situ Hybridization

  8. F.I.S.H.Fluorescence In Situ Hybridization

  9. Spectral Karyotyping (“SKY”)

  10. Spectral Karyotyping (“SKY”)Look good – anything wrong?

  11. Spectral Karyotyping (“SKY”)Look good – anything wrong?

  12. We can even locate a gene on a chromosome

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