1 / 2

Functional CXCR4 and CCR5 in EBV Transformation

The study investigates how CXCR4 and CCR5 affect EBV transformation efficiency in cell lines. CXCR4 plays a role in both Type 1 and 2 transformation, while CCR5 may suppress Type 1 transformation due to signal transduction defects.

illana-wong
Télécharger la présentation

Functional CXCR4 and CCR5 in EBV Transformation

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. a-CD3 A. PM1 C. RANTES MIP-1b Ionomycin a-CD3 B. PBMCs RANTES MIP-1b Functional CXCR4 is present on all cell lines; CCR5 is either absent, or defective in signal transduction.

  2. X4 gp20 enhances Type 1 & 2 EBV transformation; R5 may suppress Type 1 transformation Low efficiency AG876 High efficiency B95.8 Low efficiency AG876 c

More Related