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Kognitiv Neurovidenskab og dens Metoder

Kognitiv Neurovidenskab og dens Metoder. Søren Kyllingbæk. Transkraniel Magnetisk Stimulation. TMS. TMS. K. Tid. Neurofysiologiske Målinger. Neurofysiologiske Målinger. Neurofysiologiske Målinger. Preferred. Non-preferred. Moran and Desimone (1985). Preferred. Non-preferred.

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Kognitiv Neurovidenskab og dens Metoder

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  1. Kognitiv Neurovidenskab og dens Metoder Søren Kyllingbæk

  2. Transkraniel Magnetisk Stimulation

  3. TMS

  4. TMS K Tid

  5. Neurofysiologiske Målinger

  6. Neurofysiologiske Målinger

  7. Neurofysiologiske Målinger

  8. Preferred Non-preferred Moran and Desimone (1985)

  9. Preferred Non-preferred Moran and Desimone (1985) Attention Attention

  10. Preferred Non-preferred Moran and Desimone (1985) Attention Attention

  11. A Neural Theory of Visual AttentionBundesen, Habekost, & Kyllingsbæk (2005) • Bridging the gap between cognition and neurophysiology. • A unified mathematical approach • Neural network model

  12. Neural Theory of Visual Attention(Bundesen, Habekost, Kyllingsbæk, 2005)

  13. Elektroencephalografi (EEG)Event Related Potentials (ERP)

  14. EEG/ERP

  15. EEG/ERP

  16. EEG/ERP • -100 til +100 μV • 0 til 40 Hz • Epoch (låst i tid til stimulus) • => Event Related Potential (ERP)

  17. EEG/ERP • Kilde: elektrisk felt omkring population af neuroner • Stor population • Synkron fyring • Post synaptisk aktivitet • Konfiguration som åbent dipol felt • ”Usynlig” aktivitet: lukket, svagt, asynkron felt

  18. EEG/ERP • Åbent / lukket felt

  19. Elektrodeopsætning10-20 systemet

  20. Elektrodeopsætning10-20 systemet Reference elektroder - linked mastoid

  21. Signalet i de Enkelte Elektroder

  22. ERP

  23. ERP

  24. ERP

  25. ERP - frekvensfiltrering

  26. ERP • Artefakter • Øjenbevægelser • Blink • Fastholdt fiksation => sekundær aktivitet • Bortsortering af data => manglende data • Estimation og bortfiltrering

  27. ERP • Signal behandling • EEG -/+ 100 μV (støj) • ERP -/+ 5 μV (signal) => Midling • Problemer: bimodal fordeling • Amplityde • Latenstid

  28. ERP - midling

  29. ERP komponenter • Definition • Anatomisk • Psykologisk • Tidslig relation • Event-preceding • Event-following

  30. ERP – readiness potential

  31. ERP- Contingent Negative Variation (CNV)

  32. ERP (O+E wave)2 rather than 1 component

  33. ERP – Nd/processing negativity

  34. N2 and Mismatch Negativity- automatic processing?!

  35. ERP – P300, P3, P3a, & P3b

  36. ERP – N400

  37. Magnetoencephalografi

  38. MEG

  39. MEG

  40. MEG

  41. MEG

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