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Advancements in Growing Blood Vessels: A Study by John Rawls in Regenerative Medicine

This article explores the revolutionary work of John Rawls in regenerative medicine, focusing on innovative techniques for growing blood vessels in a lab setting. By utilizing modified polyethylene glycol (PEG) to mimic the body's extracellular matrix and combining it with essential cell types, scientists have successfully created hydrogels filled with living cells and growth factors. These engineered capillaries have been implanted in mice, revealing normal blood flow and paving the way for potential solutions to organ transplant rejection and shortages.

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Advancements in Growing Blood Vessels: A Study by John Rawls in Regenerative Medicine

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  1. Growing Blood Vessels John Rawls

  2. Regenerative Medicine • The process of replacing or regenerating human cells, tissues, or organs to restore or establish normal function • Growing tissues and organs in a lab • Implant in body successfully • Could solve the problem of organ transplant rejection and the shortage of organs • Stem Cells

  3. Polyethylene Glycol • Also called PEG and Carbowax • Nontoxic plastic • Scientists modify PEG to mimic the body’s extracellular matrix • Combined with two types of cells required of blood vessel formation • Creates hydrogels filled with living cells and growth factors

  4. The Result • Cells are tagged with fluorescent markers • Created capillaries and vessels • Successfully implanted in mice • Normal blood flow recorded

  5. What is to become? • Current method of creating blood vessels takes too much time • Other ways to create blood vessels and capillaries are being researched • “Two-photon liphography” • Allows more control

  6. Refrences • http://esciencenews.com/articles/2011/01/12/biomedical.breakthrough.blood.vessels.lab.grown.tissues • http://www.sciencedaily.com/releases/2011/01/110112080910.htm • http://www.aaas.org/news/releases/2011/0202sp_vessels.shtml • http://www.futuremedicine.com/loi/rme • http://en.wikipedia.org/wiki/Regenerative_medicine • http://en.wikipedia.org/wiki/Polyethylene_glycol • http://sojor.net/photoUploads/User1309196521.jpg

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