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Microbial Therapy (Steph, Alex, Sammy) Pathway Engineering

Brainstorming Session Overview : Useful Applications of Synthetic Biology. Medical / Human Applications. BioEnergy. Microbial Therapy (Steph, Alex, Sammy) Pathway Engineering - make product body needs (possibly sense deficiency) - Synthetic Symbiosis

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Microbial Therapy (Steph, Alex, Sammy) Pathway Engineering

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  1. Brainstorming Session Overview: Useful Applications of Synthetic Biology Medical / Human Applications BioEnergy Microbial Therapy (Steph, Alex, Sammy) Pathway Engineering - make product body needs (possibly sense deficiency) - Synthetic Symbiosis (E. coli natural gut environment) - Vitamin B Production (Steph and Alex) - Fibrin (clotting) (Sammy) - Insulin (Harris) - Degrade Plaque - Implantable Devices that release or synthesize drugs - Off-switch for safety, competitive concerns (Alex) Cellular Targeting - Aptamers (Steph) - Bacterial Surface Display / Fusion Prot. (Perry) - Target Bact to certain tissues (actuator or product) - Targeting Microbial Factories - Sequestration of Toxic Compounds (Sammy) Bacterial Biosensors - Sense and Sequester Toxic Compounds (arsenic) (Sammy) - Quorum Sensing - Radon Sensor Biofilms and Vascularization (Harris and Sammy) Recombination (Harris) Producing a Renewable Energy Source Cellulose to EtOH (Shaunak, Steph, Alex) Fatty Acid production and degradation for energy Synthesis, Tolerance, and Export of EtOH or alkanes Alternative organisms for Energy Prod. Yeast (Shaunak) Bacteria as Energy Source Light Powering E. coli w/ Photorhodopsin (Alex) Powering Implantable Medical Devices Light sensitive Proton Pump (Pseud. Putida) Biological Based Fuel Cells (Sammy) Bridging Applications E. coli that resists mutations (Alex) Cellular Computation (George) Microfluidics (George) DNA transfer using virus (Shaunak) Combinatorial Constructions and Selections BioBricks (Nick)

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