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The SARC Sarcoma SPORE: A Unique Collaborative (Ad)venture

The SARC Sarcoma SPORE, led by Dr. Raphael E. Pollock at the University of Texas MD Anderson Cancer Center, embodies a collaborative framework for sarcoma research involving adult and pediatric projects. This initiative focuses on interdisciplinary, translational research that integrates basic and applied science. Key features include multiple joint projects, specialized CORE support, access to diverse cancer patient populations, and substantial involvement from well-established researchers. The SPORE promotes innovation in prevention, detection, diagnosis, and treatment of sarcomas, ensuring continuous development and collaboration.

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The SARC Sarcoma SPORE: A Unique Collaborative (Ad)venture

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  1. The SARC Sarcoma SPORE: A Unique Collaborative (Ad)venture Raphael E. Pollock, MD, PhD Department of Surgical Oncology Division of Surgery University of Texas MD Anderson Cancer Center Houston, Texas

  2. Introduction Specialized Programs of Research Excellence (SPOREs) are specialized center grants to support multi-project, interdisciplinary, and in some cases, multi-institutional, translational research involving both basic and applied scientists that will result in diverse new approaches to the prevention, early detection, diagnosis and treatment of human cancers.

  3. SPORE key features/requirements 1. Multiple projects (four minimum), each co-led by a basic and applied/clinical scientist 2. Specialized shared COREs to support the projects 3. Flexibility to terminate projects that are not meeting translational goals and to replace them with new promising projects 4. Inter-SPORE collaboration or collaboration with other research groups that combine resources and expertise

  4. SPORE key features/requirements 5. Substantial access to cancer patient populations 6. Investigators who have a strong, demonstrable research base in the cancer type to be studied 7. Creation of programs to develop pilot projects and also help to develop translational scientists

  5. The SARC Sarcoma SPORE

  6. SARC Sarcoma SPORE unique features Adult and pediatric projects Sponsored by a professional organization (SARC) NCI intramural investigator involvement Three major performance sites (MDACC, UM, HCC)

  7. SARC Sarcoma SPORE Research Projects

  8. The SPORE Research Support COREs

  9. Career Development Program

  10. Developmental Research Project Program

  11. After three separate submissions/reviews (2009-2012), all’s well that ends well...

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