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This article delves into the intricate processes of pre-mRNA and mRNA maturation, highlighting the significance of the TIM (Translocase of the Inner Mitochondrial Membrane) and PDP1 (Protein Degradation Pathway 1) proteins. We explore how these factors influence gene expression and the various post-transcriptional modifications that occur. By understanding the interactions between pre-mRNA, mRNA, and their processing machinery, we gain insights into the regulatory mechanisms underlying cellular function and the potential implications for disease models.
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E-box E-box E-box E-box E-box X-P PERnpp X-Pp PERpp X-Ppp PERnp PERp dCLKn PERn per pre-mRNA per mRNA PER X-PTp PERp-TIMp X-PpTp TIMnpp X-PppTp PERpp-TIMp X-PTpp TIMnp dCLKn X-PpTpp PERp-TIMpp TIM tim mRNA tim pre-mRNA X-PppTp X-PppTpp X-PppTp PERpp-TIMpp PERn-TIMnp dCLKn TIMp PERnp-TIMnp TIMpp dCLKn PERnpp-TIMnp VRI VRIp vri pre-mRNA vri mRNA PERn-TIMnpp PERnp-TIMnpp dCLKn PDP1p pdp1 pre-mRNA pdp1 mRNA PDP1 PERnpp-TIMnpp dCLKn PDP1n dCLKp VRIn dCLKpp dClk pre-mRNA dClk mRNA dCLK PDP1pn dCLKp VRIpn dCLKpp