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Emerging Technologies

Emerging Technologies. Semantic Web and Data Integration This meeting will start at 5 min past the hour As a reminder, please place your phone on mute unless you are speaking. 18 Oct 2013. Meeting Agenda. Representing CDISC Standards in RDF - Update

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Emerging Technologies

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  1. Emerging Technologies Semantic Web and Data Integration This meeting will start at 5 min past the hour As a reminder, please place your phone on mute unless you are speaking 18 Oct 2013

  2. Meeting Agenda Representing CDISC Standards in RDF - Update Team CDISC Conformance Checks in RDF – Update Team Protocol Representation in RDF – Update PhUSE Conference Brussels AOB

  3. Representing CDISC Standards in RDF

  4. Representing CDISC Standards in RDF Deliverables: CDASH v1.1 including domain assumptions SDTM v1.2/SDTM v3.1.2 including domain assumptions SDTM v1.3/SDTM v3.1.3 including domain assumptions SEND IG v3.0 including domain assumptions ADaM v2.1/ADaM IG v1.0 Integrate with Controlled Terminology

  5. Deliverables

  6. Schema Structure Meta-Model Schema Controlled Terminology Schema CDISC Schema ADaM Schema CDASH Schema SDTM Schema SEND Schema ADaM CDASH SDTM SEND

  7. SDTM Walk-Through

  8. SDTM Walk-Through

  9. SDTM Walk-Through

  10. SDTM Walk-Through

  11. SDTM Walk-Through

  12. SDTM Walk-Through

  13. Finishing Line • Update a few remaining namespaces for consistency • Final check of the CDISC schema • Final check of the domain assumptions • Consistent formatting of the import files • Dirty work • typo’s, trailing blanks, non-ASCII characters etc. • Code repository • github.com/phuse-org/rdf.cdisc.org

  14. GitHub Repository

  15. Next Steps Call for review of draft models Discuss ownership process with CDISC Discuss SHARE export facility to RDF Alignment and final edit

  16. Representing CDISC Conformance Checks in RDF Scott Bahlavooni and Josephine Gough Protocol Representation in RDF Geoff Low and Frederik Malfait New Teams Starting…

  17. Representing and Accessing Clinical Trial Data in RDF Tentative: Phil Ashworth and Marc Andersen Data Analysis and Reporting Model To be explored Representing Regulations and Guidance in RDF Status to be discussed EHR Enabled Research To be explored Pipeline

  18. Representing Conformance Checks in RDFBackup Slides

  19. Represent SDTM and ADaM validation rules in RDF Implementation algorithms will not be represented Objective

  20. ADaM standard includes validation rules Identifying all validation rules associated with an SDTM (ADaM) domain or variable is a non-trivial, manual task Vendor-agnostic representation of SDTM validation rules Rationale

  21. Define an ontology for validation rules Identify version(s) of SDTM/ADaM validation rules for representation Link the RDF representations to CDISC standards represented in RDF Deliverables

  22. Protocol Representation in RDF

  23. Tasks Represent Schedule of Assessments in RDF Represent Trial Design in RDF Represent the PRM in RDF

  24. Challenges PRM primarily BRIDG based, unlike CDASH/SDTM End of Year, deadlines

  25. Approach Read and understand Study Design Model (XML) Protocol Representation Model (PRM) Identify key components Classes Properties Model using XLSX and TopBraid

  26. Approach (cont.) Consultation Dave Gemzik (head of PRG) Expectations ~ 1hr + 1hr Communication PhUSE Wiki Email Team meetings

  27. PhUSE Conference Brussels

  28. What happened More people talking about RDF and Linked Data Presentation Semantic Technology and CDISC Standards PhUSE CSS Discussion Club

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