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22 PART 1

22 PART 1. The Respiratory System Pages 645-665. The Respiratory System. Basic functions of the respiratory system Supplies body with oxygen Disposes of carbon dioxide Four processes involved in respiration Pulmonary ventilation External respiration Transport of respiratory gases

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22 PART 1

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  1. 22 PART 1 The Respiratory System Pages 645-665

  2. The Respiratory System • Basic functions of the respiratory system • Supplies body with oxygen • Disposes of carbon dioxide • Four processes involved in respiration • Pulmonary ventilation • External respiration • Transport of respiratory gases • Internal respiration

  3. Functional Anatomy of the Respiratory System • Respiratory organs • Nose, nasal cavity, and paranasal sinuses • Pharynx, larynx, and trachea • Bronchi and smaller branches • Lungs and alveoli

  4. Nasal cavity Oral cavity Pharynx Nostril Left main (primary) bronchus Larynx Bronchi Trachea Carina of trachea Alveoli Right main (primary) bronchus Left lung Right lung Diaphragm Parietal pleura Organs of the Respiratory System Figure 22.1

  5. Organs of the Respiratory System • Divided into • Conducting zone • Respiratory zone

  6. The Nose • Provides an airway for respiration • Moistens and warms air • Filters inhaled air • Resonating chamber for speech • Houses olfactory receptors

  7. Frontal bone Epicranius, frontal belly Nasal bone Septal cartilage Root and bridge of nose Maxillary bone (frontal process) Lateral process of septal cartilage Dorsum nasi Minor alar cartilages Ala of nose Dense fibrous connective tissue Apex of nose Naris (nostril) Major alar cartilages Philtrum (a) Surface anatomy (b) External skeletal framework The Nose • Size variation due to differences in nasal cartilages • Skin is thin—contains many sebaceous glands Figure 22.2

  8. The Nasal Cavity • External nares—nostrils • Divided by nasal septum • Continuous with nasopharynx • Posterior nasal apertures—choanae

  9. Nasal Cavity • Two types of mucous membrane • Olfactory mucosa • Near roof of nasal cavity • Houses olfactory (smell) receptors • Respiratory mucosa • Lines nasal cavity • Epithelium is pseudostratified ciliated columnar

  10. Cribriform plate of ethmoid bone Frontal sinus Sphenoid sinus Nasal cavity Posterior nasal aperture Nasal conchae (superior, middle and inferior) Nasopharynx Pharyngeal tonsil Nasal meatuses (superior, middle, and inferior) Opening of pharyngotympanic tube Nasal vestibule Nostril Uvula Oropharynx Hard palate Palatine tonsil Soft palate Isthmus of the fauces Tongue Lingual tonsil Laryngopharynx Hyoid bone Larynx Epiglottis Vestibular fold Esophagus Thyroid cartilage Vocal fold Trachea Cricoid cartilage Thyroid gland (c) Illustration The Upper Respiratory Tract Figure 22.3

  11. Nasal Conchae • Superior and middle nasal conchae • Part of the ethmoid bone • Inferior nasal conchae • Separate bone • Project medially from the lateral wall of the nasal cavity

  12. The Pharynx • Funnel-shaped passageway • Connects nasal cavity and mouth • Divided into three sections by location • Nasopharynx • Oropharynx • Laryngopharynx • Type of mucosal lining changes along its length

  13. Cribriform plate of ethmoid bone Frontal sinus Sphenoid sinus Nasal cavity Posterior nasal aperture Nasal conchae (superior, middle and inferior) Nasopharynx Pharyngeal tonsil Nasal meatuses (superior, middle, and inferior) Opening of pharyngotympanic tube Nasal vestibule Nostril Uvula Oropharynx Hard palate Palatine tonsil Soft palate Isthmus of the fauces Tongue Lingual tonsil Laryngopharynx Hyoid bone Larynx Epiglottis Vestibular fold Esophagus Thyroid cartilage Vocal fold Trachea Cricoid cartilage Thyroid gland (c) Illustration The Upper Respiratory Tract Figure 22.3

  14. The Nasopharynx • Superior to the point where food enters • Only an air passageway • Closed off during swallowing • Pharyngeal tonsil (adenoids) • Located on posterior wall • Destroys entering pathogens • Contains the opening to the pharyngotympanic tube (auditory tube)

  15. The Oropharynx • Arch-like entranceway—fauces • Extends from soft palate to the epiglottis • Epithelium • Stratified squamous epithelium • Two types of tonsils in the oropharynx • Palatine tonsils—in the lateral walls of the fauces • Lingual tonsils—covers the posterior surface of the tongue

  16. Cribriform plate of ethmoid bone Frontal sinus Sphenoid sinus Nasal cavity Posterior nasal aperture Nasal conchae (superior, middle and inferior) Nasopharynx Pharyngeal tonsil Nasal meatuses (superior, middle, and inferior) Opening of pharyngotympanic tube Nasal vestibule Nostril Uvula Oropharynx Hard palate Palatine tonsil Soft palate Isthmus of the fauces Tongue Lingual tonsil Laryngopharynx Hyoid bone Larynx Epiglottis Vestibular fold Esophagus Thyroid cartilage Vocal fold Trachea Cricoid cartilage Thyroid gland (c) Illustration The Upper Respiratory Tract Figure 22.3

  17. The Laryngopharynx • Passageway for both food and air • Epithelium • Stratified squamous epithelium • Continuous with the esophagus and larynx

  18. The Larynx • Three functions • Voice production • Provides an open airway • Routes air and food into the proper channels • Superior opening is • Closed during swallowing • Open during breathing

  19. Cribriform plate of ethmoid bone Frontal sinus Sphenoid sinus Nasal cavity Posterior nasal aperture Nasal conchae (superior, middle and inferior) Nasopharynx Pharyngeal tonsil Nasal meatuses (superior, middle, and inferior) Opening of pharyngotympanic tube Nasal vestibule Nostril Uvula Oropharynx Hard palate Palatine tonsil Soft palate Isthmus of the fauces Tongue Lingual tonsil Laryngopharynx Hyoid bone Larynx Epiglottis Vestibular fold Esophagus Thyroid cartilage Vocal fold Trachea Cricoid cartilage Thyroid gland (c) Illustration The Upper Respiratory Tract Figure 22.3

  20. Nine Cartilages of the Larynx • Thyroid cartilage • Shield-shaped, forms laryngeal prominence (Adam’s apple) • Three pairs of small cartilages • Arytenoid cartilages • Corniculate cartilages • Cuneiform cartilages • Epiglottis • Tips inferiorly during swallowing

  21. Body of hyoid bone Laryngeal prominence (Adam’s apple) Cricoid cartilage Sternal head Clavicular head Sternocleidomastoid Clavicle Jugular notch (a) Surface view Epiglottis Thyrohyoid membrane Body of hyoid bone Thyroid cartilage Laryngeal prominence (Adam’s apple) Cricothyroid ligament Cricoid cartilage Cricotracheal ligament Tracheal cartilages (b) Anterior view Anatomy of the Larynx Figure 22.5a, b

  22. Epiglottis Hyoid bone Thyrohyoid membrane Corniculate cartilage Arytenoid cartilage Thyroid cartilage Cricoid cartilage Glottis Tracheal cartilages (c) Photograph of cartilaginous framework of the larynx, posterior view Epiglottis Thyrohyoid membrane Body of hyoid bone Thyrohyoid membrane Cuneiform cartilage Fatty pad Vestibular fold (false vocal cord) Corniculate cartilage Arytenoid cartilage Thyroid cartilage Arytenoid muscle Vocal fold (true vocal cord) Cricoid cartilage Cricothyroid ligament Cricotracheal ligament Tracheal cartilages (d) Sagittal section (anterior on the right) Anatomy of the Larynx Figure 22.5c, d

  23. The Larynx • Vocal ligaments of the larynx • Vocal folds (true vocal cords) • Act in sound production • Vestibular folds (false vocal cords) • No role in sound production • Epithelium of the larynx • Stratified squamous—superior portion • Pseudostratified ciliated columnar—inferior portion

  24. Anterior Thyroid cartilage Cricoid cartilage Vocal ligaments of vocal cords Glottis Lateral cricoarytenoid muscle Arytenoid cartilage Corniculate cartilage Posterior cricoarytenoid muscle Posterior Base of tongue Epiglottis Vestibular fold (false vocal cord) Vocal fold (true vocal cord) Glottis Inner lining of trachea Cuneiform cartilage Corniculate cartilage (a) Vocal folds in closed position; closed glottis (b) Vocal folds in open position; open glottis Movements of the Vocal Folds Figure 22.6

  25. The Trachea • Descends into the mediastinum • C-shaped cartilage rings keep airway open • Carina • Marks where trachea divides into two primary bronchi • Epithelium • Pseudostratified ciliated columnar

  26. Nasal cavity Oral cavity Pharynx Nostril Left main (primary) bronchus Larynx Bronchi Trachea Carina of trachea Alveoli Right main (primary) bronchus Left lung Right lung Diaphragm Parietal pleura Organs of the Respiratory System Figure 22.1

  27. Posterior Mucosa Pseudostratified ciliated columnar epithelium Lamina propria (connective tissue) Mucosa Submucosa Esophagus Submucosa Seromucous gland in submucosa Trachealis muscle Seromucous gland in submucosa Lumen of trachea Hyaline cartilage Hyaline cartilage Adventitia Anterior (a) Cross section of the trachea and esophagus (b) Photomicrograph of the tracheal wall (250) The Trachea Figure 22.7

  28. Bronchi in the Conducting Zone • Bronchial tree • Extensively branching respiratory passageways • Primary bronchi (main bronchi) • Largest bronchi • Right main bronchi • Wider and shorter than the left

  29. Superior lobe of right lung Trachea Superior lobe of left lung Left main (primary) bronchus Lobar (secondary) bronchus Segmental (tertiary) bronchus Inferior lobe of left lung Middle lobe of right lung Inferior lobe of right lung (a) The branching of the bronchial tree Bronchi in the Conducting Zone Figure 22.8a

  30. Bronchi in the Conducting Zone • Secondary (lobar) bronchi • Three on the right • Two on the left • Tertiary (segmental) bronchi • Branch into each lung segment • Bronchioles • Little bronchi, less than 1 mm in diameter • Terminal bronchioles • Less than 0.5 mm in diameter

  31. Figure 22.12 Bronchopulmonary segments. Lingular Apicoposterior Apical Anterior Superior Superior Posterior Anterior Superior Inferior Lateral Middle Medial Superior Anterior basal Superior Inferior Anterior basal Medial basal Medial basal Inferior Lateral basal Lateral basal Posterior basal Posterior basal Segmental bronchi Superior lobe Apical Superior lobe Superiordivision Posterior Apical Anterior Posterior Anterior Superiorlingular Lingulardivision Middle lobe Inferiorlingular Lateral Medial Inferior lobe Superior Inferior lobe Anterior basal Superior Lateral basal Anterior basal Lateral basal Left lung Right lung Distribution of bronchiopulmonary segments on lateral surface of lungs

  32. Changes in Tissue Composition along Conducting Pathways • Supportive connective tissues change • C-shaped rings replaced by cartilage plates • Epithelium changes • First, pseudostratified ciliated columnar • Replaced by simple columnar, then simple cuboidal epithelium • Smooth muscle becomes important • Airways widen with sympathetic stimulation • Airways constrict under parasympathetic direction

  33. Figure 22.8b The bronchi in the conducting zone. Mucosa Pseudostratifiedepithelium Lamina propria Fibromusculo-cartilaginous layer Lumen Cartilage plate Smooth muscle Photomicrograph of a bronchus (35)

  34. Structures of the Respiratory Zone • Consists of air-exchanging structures • Respiratory bronchioles—branch from terminal bronchioles • Lead to alveolar ducts • Lead to alveolar sacs

  35. Alveoli Alveolar duct Respiratory bronchioles Alveolar duct Terminal bronchiole Alveolar sac (a) Structures of the Respiratory Zone Figure 22.9a

  36. Figure 22.9b Structures of the respiratory zone. Respiratorybronchiole Alveolarpores Alveolarduct Alveoli Alveolarsac

  37. Structures of the Respiratory Zone • Alveoli • ~300 million alveoli account for tremendous surface area of the lungs • Structure of alveoli • Type I cells—single layer of simple squamous epithelial cells • Surrounded by basal lamina • Alveolar and capillary walls plus their basal lamina form • Respiratory membrane

  38. Terminal bronchiole Respiratory bronchiole Smooth muscle Elastic fibers Alveolus Capillaries (a) Diagrammatic view of capillary-alveoli relationships Anatomy of Alveoli and the Respiratory Membrane Figure 22.10a, b

  39. Red blood cell Nucleus of type I (squamous epithelial) cell Alveolar pores Capillary O2 Capillary CO2 Alveolus Macrophage Endothelial cell nucleus Alveolus Alveolar epithelium Respiratory membrane Fused basement membranes of the alveolar epithelium and the capillary endothelium Red blood cell in capillary Type I cell of alveolar wall Capillary endothelium Alveoli (gas-filled air spaces) Type II (surfactant- secreting) cell (c) Detailed anatomy of the respiratory membrane Anatomy of Alveoli and the Respiratory Membrane Figure 22.10c

  40. Structures of the Respiratory Zone • Structures of alveoli (continued) • Type II cells—scattered among type I cells • Are cuboidal epithelial cells • Secrete surfactant • Reduces surface tension within alveoli • Alveolar macrophages

  41. Gross Anatomy of the Lungs • Major landmarks of the lungs • Apex, base, hilum, and root • Left lung • Superior and inferior lobes • Fissure—oblique • Right lung • Superior, middle, and inferior lobes • Fissures—oblique and horizontal

  42. Intercostal muscle Apex of lung Rib Parietal pleura Lung Pleural cavity Pulmonary artery Visceral pleura Trachea Thymus Left main bronchus Left superior lobe Apex of lung Left superior lobe Oblique fissure Pulmonary vein Right superior lobe Oblique fissure Horizontal fissure Left inferior lobe Impression of heart Left inferior lobe Right middle lobe Oblique fissure Oblique fissure Hilum Right inferior lobe Heart (in mediastinum) Aortic impression Lobules Diaphragm (b) Photograph of medial view of the left lung Cardiac notch Base of lung (a) Anterior view. The lungs flank mediastinal structures laterally. Gross Anatomy of the Lungs Anterior View of Thoracic Structures Figure 22.11a, b

  43. Intercostal muscle Rib Parietal pleura Lung Pleural cavity Visceral pleura Trachea Thymus Apex of lung Left superior lobe Right superior lobe Oblique fissure Horizontal fissure Left inferior lobe Right middle lobe Oblique fissure Right inferior lobe Heart (in mediastinum) Diaphragm Cardiac notch Base of lung (a) Anterior view. The lungs flank mediastinal structures laterally. Figure 22.11a

  44. Blood Supply and Innervation of the Lungs • Pulmonary arteries • Deliver oxygen-poor blood to the lungs • Pulmonary veins • Carry oxygenated blood to the heart

  45. Posterior Esophagus (in mediastinum) Vertebra Root of lung at hilum Right lung Left main bronchus Left pulmonary artery Parietal pleura Left pulmonary vein Visceral pleura Left lung Pleural cavity Thoracic wall Pulmonary trunk Pericardial membranes Heart (in mediastinum) Anterior mediastinum Sternum Anterior (d) Transverse section through the thorax, viewed from above. Lungs, pleural membranes, and major organs in the mediastinum are shown. Transverse Cut through the Superior Thorax Figure 22.11d

  46. The Pleurae • A double-layered sac surrounding each lung • Parietal pleura • Visceral pleura • Pleural cavity • Space between the visceral and parietal pleurae • Pleurae help divide the thoracic cavity • Central mediastinum • Two lateral pleural compartments

  47. Intercostal muscle Rib Parietal pleura Lung Pleural cavity Visceral pleura Trachea Thymus Apex of lung Left superior lobe Right superior lobe Oblique fissure Horizontal fissure Left inferior lobe Right middle lobe Oblique fissure Right inferior lobe Heart (in mediastinum) Diaphragm Cardiac notch Base of lung (a) Anterior view. The lungs flank mediastinal structures laterally. Diagram of the Pleurae and Pleural Cavities Figure 22.11a

  48. The Mechanisms of Ventilation • Two phases of pulmonary ventilation • Inspiration—inhalation • Expiration—exhalation

  49. Inspiration • Volume of thoracic cavity increases • Decreases internal gas pressure • Action of the diaphragm • Diaphragm flattens • Action of intercostal muscles • Contraction raises the ribs

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