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This study investigates the effects of RNA polymerase (RNAP) mutations and the heterologous T7 RNAP, alongside tagetitoxin (Tgt), on Rho-mediated transcription termination in bacteria. By analyzing how these factors influence termination efficiency, the research provides insights into the molecular mechanisms governing transcription regulation. The findings reveal the intricate interplay between RNAP mutations and Rho factors, offering a deeper understanding of transcription termination processes and their biological significance.
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Effect of RNAP mutations, heterologous (T7) RNAP and tagetitoxin (Tgt) on Rho termination. V Epshtein et al. Nature463, 245-249 (2010) doi:10.1038/nature08669